Results 191 to 200 of about 2,153,844 (234)
Are Low-to-Moderate Average Alcohol Consumption and Isolated Episodes of Binge Drinking in Early Pregnancy Associated with Facial Features Related to Fetal Alcohol Syndrome in 5-Year-Old Children? [PDF]
Kesmodel US +6 more
europepmc +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source
Clinical Epigenomics in Rare Diseases: Interpreting DNA Methylation Episignatures
Clinical epigenomics extends rare‐disease diagnostics beyond DNA sequence by revealing the downstream regulatory consequences of genetic variation. DNA methylation episignatures provide functional evidence that can support diagnosis, refine variant interpretation, distinguish overlapping disorders, and complement genomic, and multi‐omic testing ...
Himanshu Goel, Shuxiang Goh, Luke Stuart
wiley +1 more source
Factors Associated With Menopause Symptoms: A Systematic Review and Meta‐Analysis
ABSTRACT Background Menopause, marked by hormonal decline and menstrual cessation, is associated with various symptoms. Socio‐demographic and behavioural factors may influence symptom type and severity. Understanding these associations can inform better symptom management.
Janice Hoang +10 more
wiley +1 more source
What Do We Know About Alcohol Consumption During Pregnancy and Fetal Alcohol Spectrum Disorder in Nigeria? A Narrative Review [PDF]
ABSTRACT Background and Aims Alcohol consumption during pregnancy poses notable risks to maternal and foetal health, yet its prevalence and impact in Nigeria remain understudied. This narrative review aims to initiate conversations around the current state of alcohol intake by expectant mothers in Nigeria and Fetal Alcohol Spectrum Disorder (FASD ...
Azumara S +4 more
europepmc +2 more sources
Progerin accumulation downregulates the expression of m6A methyltransferases METTL3 and METTL14 in cardiac tissues, impairing m6A modification‐mediated regulation of target genes including Casq2, Ifna and Ifnb, leading to calcium signaling dysregulation and pro‐inflammatory activation in the aged heart.
Shixiao Wang +17 more
wiley +1 more source
Fetal alcohol syndrome: dashed hopes, damaged lives
doaj +1 more source
ABSTRACT Background There are gaps in understanding females' beliefs related to chronic pelvic pain. Beliefs might be linked to illness perceptions and behaviours. Aims (1) Explore beliefs and experiences of Australian females living with chronic pelvic pain, against categories based on clinical guidelines.
Emma Wise +5 more
wiley +1 more source
Developmental stuttering with common and complex phenotypes
Abstract Aim To describe the phenotypic spectrum associated with stuttering. Method Individuals with current or resolved developmental stuttering self‐referred. Surveys assessed stuttering characteristics (onset, negative impact, family history) and health (early development, other conditions).
Sarah E. Horton +6 more
wiley +1 more source

