Results 211 to 220 of about 112,777 (291)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Fetal alcohol syndrome surveillance: age of syndrome manifestation in case ascertainment. [PDF]

Birth Defects Res A Clin Mol Teratol, 2014
Moberg DP, Bowser J, Burd L, Elliott AJ, Punyko J, Wilton G, Fetal Alcohol Syndrome Surveillance Program-FASSLink Team.   +6 more
europepmc   +1 more source

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Effect of boric acid on oxidative stress in rats with fetal alcohol syndrome. [PDF]

Exp Ther Med, 2015
Sogut I, Oglakci A, Kartkaya K, Ol KK, Sogut MS, Kanbak G, Inal ME.   +6 more
europepmc   +1 more source

Nobody made the connection : the prevalence of neurodisability in young people who offend [PDF]

, 2012
Hughes, Nathan
core  

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

Advanced Science, Volume 13, Issue 25, 4 May 2026.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang, Maodong Leng, Chenchen Sun, Jingyu Cao, Linfei Li, Yangyang Jia, Yongshuai Han, Yuchun Liu, Yaodong Zhang, Chenglong Zhang, Yingli Men, Ningyuan Liu, Yibing Cheng, Yixia Zhang, Ya Li, Zhenlong Li, Lidan Cui, Xiangzhan Zhu   +17 more
wiley   +1 more source

Renal dysfunction in fetal alcohol syndrome: a potential contributor on developmental disabilities of offspring. [PDF]

J Renal Inj Prev, 2014
Assadi F.
europepmc   +1 more source

Sirenomelia: A Review of European Prevalence Data and Epidemiological Analysis of 17 Cases Registered in Wales

Birth Defects Research, Volume 118, Issue 5, May 2026.
ABSTRACT Background Sirenomelia is a rare congenital condition most notably characterized by a single lower limb. Previous studies have suggested a prevalence of approximately 1 per 100,000 births. However, in Wales 17 cases were recorded between 1998 and 2016, suggesting a higher rate of sirenomelia in this country.
Chris Emmerson, Michael Olson, Ceri Williams, Robert Maddison, David Tucker, Llion Davies, Annie Perraud, Linda Bailey, Ciarán Humphreys, Rhian Hughes, Joanna Sichitiu, Madalen Oribe Amores, Ingeborg Barisic, Michele Santoro, Clara Cavero Carbonell, Elizabeth S. Draper, Martin Haeusler, Isabelle Monier, Anna Latos‐Bielenska, Carlos Matias Dias, Elly Den Hond, Elisa Ballardini, Mary O'Mahony, Isabelle Perthus, Judith Rankin, Anke Rissmann, Florence Rouget, Sarah Stevens, Jorieke E. H. Bergman, Diana Wellesley, Wladimir Wertelecki   +30 more
wiley   +1 more source

Exploring the feasibility of using electronic health records in the surveillance of fetal alcohol syndrome. [PDF]

Birth Defects Res A Clin Mol Teratol, 2014
Hansen C, Adams M, Fox DJ, O'Leary LA, Frías JL, Freiman H, Meaney FJ.   +6 more
europepmc   +1 more source

Maternal Fish Intake in the Year Prior to Conception and Birth Defects, National Birth Defects Prevention Study, 1997–2011

Birth Defects Research, Volume 118, Issue 5, May 2026.
ABSTRACT Background Epidemiologic data on the association between maternal fish intake and birth defects are sparse. Our objective was to assess associations between maternal fish intake and 52 different birth defects, most of which have not been assessed previously.
Dorothy Kim Waller, Zeyu Miao, Renata H. Benjamin, Richard Finnell, Nithya Lakshmi Mohan Dass, Eirini Nestoridi, Marcia C. de Oliveira Otto, Julie Peterson, Tunu Ramadhani, Mark A. Canfield, the National Birth Defects Prevention Study   +10 more
wiley   +1 more source