Results 71 to 80 of about 775,984 (312)

Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates. [PDF]

, 2018
Zika virus (ZIKV) infection is associated with congenital defects and pregnancy loss. Here, we found that 26% of nonhuman primates infected with Asian/American ZIKV in early gestation experienced fetal demise later in pregnancy despite showing few ...
Aagaard, Kjersti M, Adams Waldorf, Kristina M, Ardeshir, Amir, Bliss-Moreau, Eliza, Bohm, Rudolf P, Capuano, Saverio V, Chiu, Charles Y, Coffey, Lark L, Colgin, Lois M, Dudley, Dawn M, Friedrich, Thomas C, Gale, Michael, Gilbert, Margaret H, Golos, Thaddeus G, Grigsby, Peta L, Hirsch, Alec J, Hodge, Travis, Hotchkiss, Charlotte E, Keesler, Rebekah I, MacAllister, Rhonda P, Maness, Nicholas J, Martín, Claudia Sánchez-San, Mejia, Andres, Mohr, Emma L, O'Connor, David H, Panganiban, Antonito T, Patterson, Jean L, Pecoraro, Heidi L, Rajagopal, Lakshmi, Seferovic, Maxim, Simmons, Heather A, Steinbach, Rosemary J, Streblow, Daniel N, Tamhankar, Manasi, Tardif, Suzette, Van Rompay, Koen K, Veazey, Ronald S, Wang, Xiaolei   +37 more
core  

Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering. [PDF]

, 2019
Prenatal stem cell-based regenerative therapies have progressed substantially and have been demonstrated as effective treatment options for fetal diseases that were previously deemed untreatable. Due to immunoregulatory properties, self-renewal capacity,
Farmer, Diana L, Guo, Fuzheng, Hao, Dake, He, Chuanchao, Lankford, Lee, Ma, Bowen, Reynaga, Lizette, Wang, Aijun   +7 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Teratogenic test of Pandanus conoideus var. yellow fruit extract to development of rat embryo (Rattus norvegicus) [PDF]

, 2010
Muna L, Astirin OP, Sugiyarto. 2010. Uji teratogenik ekstrak Pandanus conoideus varietas buah kuning terhadap perkembangan embrio tikus putih (Rattus norvegicus). Nusantara Bioscience 2: 126-134.
ASTIRIN, OKID PARAMA, MUNA, LINTAL, SUGIYARTO,   +2 more
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Calculation of Fetal Weight Estimation Displayed with TFT LCD [PDF]

, 2020
Fetal weight estimation during pregnancy is one of the beneficial ways to solve morbidity and death during labor problem. Manually, the fundal height is measured from the edge of the pubic symphysis to the top of the uterine fundus by following the arch ...
Mak'ruf, M. R. (M), Regitasari, N. (Nadhia), Setioningsih, E. D. (Endang)   +2 more
core  

Maternal and fetal risk factors for stillbirth : population based study [PDF]

, 2013
Objective: To assess the main risk factors associated with stillbirth in a multiethnic English maternity population. Design: Cohort study. Setting: National Health Service region in England.
Francis, A. (André), Gardosi, Jason, Madurasinghe, V., Malik, A. (Asad), Williams, M. (Mandy)   +4 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

INCIDENCIA Y FACTORES DE RIESGO ASOCIADOS AL ÓBITO FETAL EN 2 HOSPITALES VENEZOLANOS

Revista Chilena de Obstetricia y Ginecología, 2006
Objetivo: Evaluar la incidencia y factores de riesgo de óbito fetal en una población de embarazadas venezolanas. Metodología: estudio efectuado en 100 mujeres con diagnóstico de óbito fetal que acudieron al servicio de emergencia obstétrica de dos ...
Erika Rojas, Karimar Salas, Gustavo Oviedo, Geovanny Plenzyk   +3 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Reassessing the Duration of the Second Stage of Labor in Relation to Maternal and Neonatal Morbidity. [PDF]

, 2018
OBJECTIVE: To assess the morbidity associated with continuing the second-stage duration of labor, weighing the probability of spontaneous vaginal birth without morbidity compared with birth with serious maternal or neonatal complications.
Allen, Cheng, Cohen, Hamilton, Hamilton, Hellman, Laughon, Menticoglou, Moon, Myles, Rouse, Saunders, Scrucca, Spong, Zhang   +14 more
core   +2 more sources