Results 111 to 120 of about 938,719 (314)

The Role of Genes and Environment on Fetal Growth

, 2014
Fetal growth is influenced by the in utero environment and genetic factors inherited from both parents. Poor fetal growth leading to low birth weight is associated with insulin resistance and type-2 diabetes in later life.
Hillman, SL
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

The effects of asymmetric and symmetric fetal growth restriction on human capital development

This paper explores the causal pathway by which poor fetal health translates into reducing educational attainment and earnings as an adult. Using insights from the medical literature, I decompose low birth weight infants into two distinct subtypes: a ...
Robinson, Joshua J
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Effect of mindfulness group therapy on maternal psychological distress and perinatal outcomes in twin pregnancy: a randomized controlled trial

Frontiers in Psychiatry
PurposePsychosocial stress, depression, and anxiety are prevalent during pregnancy and can be associated with adverse birth outcomes. This study aimed to evaluate the effectiveness of an online Mindfulness Group Therapy (MGT) program in improving ...
Ying Zhou, Zai-Mei Tang, Lin Mei, Xiao-Chang Yang, Hong-Ling Zheng, Bi-Zhen Liao, Xin-Yang Yu   +6 more
doaj   +1 more source

Fetal Origins, Childhood Development, and Famine: A Bibliography and Literature Review [PDF]

The human costs of famines outlast the famines themselves. An increasing body of research points to their adverse long-run consequences for those born or in utero during them.
Cormac Ó Gráda
core  

Fetal and Neonatal Alloimmune Thrombocytopenia: Management and Outcome of a Large International Retrospective Cohort

, 2017
Research into fetal development and ...
Tiller, H., Westgren, M,, Tiblad, E., Kamphuis, MM, Kamphuis, M.M., Oepkes, D., Tiblad, E,, Oepkes, D, Akker, E.S. van den, Westgren, M., Tiller, H, van, den Akker ES   +11 more
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Preconception underweight impact on postnatal osteoporotic fracture: a retrospective cohort study using Japanese claims data

BMC Pregnancy and Childbirth
Background Undernutrition and underweight are osteoporosis risk factors. Therefore, improving the health of underweight young women in Japan is an important medical issue.
Kayoko Kaneko, Maiko Suto, Eiko Miyagawa, Masashi Mikami, Yukio Nakamura, Atsuko Murashima, Kenji Takehara   +6 more
doaj   +1 more source

Association between Maternal Midterm eGFR and Newborn Birth Weight

Kidney360
Key Points. Lower maternal midterm eGFR was independently associated with increased risks of low birth weight and small for gestational age. Adding eGFR to conventional risk models improved prediction of adverse birth outcomes, highlighting its value as ...
Akiko Sankoda, Naoko Arata, Yuichiro Yano, Kohei Ogawa, Nagayoshi Umehara, Asako Mito, Seiji Wada, Naho Morisaki, Yushi Ito, Haruhiko Sago, Reiko Horikawa   +10 more
doaj   +1 more source