Results 121 to 130 of about 15,951,746 (312)

The effects of asymmetric and symmetric fetal growth restriction on human capital development [PDF]

This paper explores the causal pathway by which poor fetal health translates into reducing educational attainment and earnings as an adult. Using insights from the medical literature, I decompose low birth weight infants into two distinct subtypes: a ...
Robinson, Joshua J
core  

IDB News: Vol. 3, no. 11, December 1976

, 1976
IDB News is a monthly publication of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

ZNF662 inhibits oncogenesis through NUPR1/p53 signaling pathway in epithelial ovarian cancer and is regulated by hsa-miR-429

Cellular & Molecular Biology Letters
Background Epithelial ovarian cancer (EOC) represents the most lethal malignancy of the female reproductive system, though its etiology and pathogenesis remain incompletely characterized.
Zhen Huang, Hongxue Fu, Ling Li, Wenjing Liao, Jing Zhang, Qin Tang, Mao Huang, Tingxiu Xiang, Liangdan Tang   +8 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

IDB News: Vol. 3, no. 3, April 1976

, 1976
IDB News is a monthly publication of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

Association between Maternal Midterm eGFR and Newborn Birth Weight

Kidney360
Key Points. Lower maternal midterm eGFR was independently associated with increased risks of low birth weight and small for gestational age. Adding eGFR to conventional risk models improved prediction of adverse birth outcomes, highlighting its value as ...
Akiko Sankoda, Naoko Arata, Yuichiro Yano, Kohei Ogawa, Nagayoshi Umehara, Asako Mito, Seiji Wada, Naho Morisaki, Yushi Ito, Haruhiko Sago, Reiko Horikawa   +10 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

IDB News: Vol. 1, no. 3, April 1974

, 1974
IDB News is a monthly publication of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

Preconception underweight impact on postnatal osteoporotic fracture: a retrospective cohort study using Japanese claims data

BMC Pregnancy and Childbirth
Background Undernutrition and underweight are osteoporosis risk factors. Therefore, improving the health of underweight young women in Japan is an important medical issue.
Kayoko Kaneko, Maiko Suto, Eiko Miyagawa, Masashi Mikami, Yukio Nakamura, Atsuko Murashima, Kenji Takehara   +6 more
doaj   +1 more source

Effect of mindfulness group therapy on maternal psychological distress and perinatal outcomes in twin pregnancy: a randomized controlled trial

Frontiers in Psychiatry
PurposePsychosocial stress, depression, and anxiety are prevalent during pregnancy and can be associated with adverse birth outcomes. This study aimed to evaluate the effectiveness of an online Mindfulness Group Therapy (MGT) program in improving ...
Ying Zhou, Zai-Mei Tang, Lin Mei, Xiao-Chang Yang, Hong-Ling Zheng, Bi-Zhen Liao, Xin-Yang Yu   +6 more
doaj   +1 more source