Results 51 to 60 of about 40,057 (294)

Mesencephalic Astrocyte‐Derived Neurotrophic Factor Binds BAX to Preserve Mitochondrial Homeostasis and Energy Metabolism for Relieving Myocardial Hypertrophy

Advanced Science, EarlyView.
MANF in cardiomyocytes interacts with BAX to impede BAX mitochondrial translocation and cytochrome c release, further stabilizing mitochondrial structure and energy supply to relieve myocardial apoptosis and hypertrophy, which indicates MANF as a novel cardioprotective factor to have a promising clinical application for myocardial hypertrophy ...
Dong Wang, Xinru Zhang, Baolong Wang, Haipeng Li, Dongshuo Xu, Yun Yang, Jialu Zhang, Wenbing Wang, Ren Zhang, Xinyu Wang, Yunfeng Cai, Shiyu Cao, Chao Hou, Changhui Wang   +13 more
wiley   +1 more source

Protective effects of calcyclin-binding protein against pulmonary vascular remodeling in flow-associated pulmonary arterial hypertension

Respiratory Research, 2022
Background Pulmonary arterial hypertension associated with congenital heart disease (CHD-PAH) is recognized as a cancer-like disease with a proliferative and pro-migratory phenotype in pulmonary artery smooth muscle cells (PASMCs).
Jingjing Zhou, FuRong Li, Yicheng Yang
doaj   +1 more source

A rare case of fetal cardiac hypertrophy developing into acute circulatory insufficiency and fetal compromise in type 1 diabetic pregnancy

Journal of Medical Ultrasound, 2022
Fetal cardiac hypertrophy (CH) in pregnant women with diabetes is believed to be a benign condition. We encountered a rare case of fetal CH in a pregnant woman with type 1 diabetes, which developed into severe fetal circulatory insufficiency and acidemia.
Masato Toya, Atsuhiko Sakai, Nobuhiro Hidaka, Kato Kiyoko   +3 more
doaj   +1 more source

Early Fetal Echocardiography [PDF]

Donald School Journal of Ultrasound in Obstetrics and Gynecology, 2015
ABSTRACTWithin the last decade, two significant events have contributed to the increasing interest in early fetal echocardiography. First, the introduction of high-frequency vaginal ultrasound probes allows detailed visualization of cardiac structures at early stage of gestation, making early detection of fetal malformations possible. Second, the close
Pilar Prats, Carmina Comas
openaire   +1 more source

The Role of HINT3 in Myocardial Ischemia‐Reperfusion Injury in Male Mice: Mechanisms Involving SDHA and its Acetylation

Advanced Science, EarlyView.
HINT3 expression declines after myocardial ischemia‐reperfusion injury. In male mice, loss of HINT3 worsens cardiac injury and mitochondrial dysfunction, while its overexpression is protective. HINT3 binds the mitochondrial enzyme succinate dehydrogenase (SDHA) and prevents its deacetylation by histone deacetylase 1 (HDAC1), reducing succinate ...
Jiabin Yu, Qi Yao, Tongtong Hu, Yadan Zhang, Ying Liu, Yang Xiao, Qingqing Wu, Qizhu Tang   +7 more
wiley   +1 more source

Prenatal diagnosis of accessory mitral valve tissue in a fetus with persistent dysrhythmia

The Egyptian Heart Journal, 2022
Background Accessory mitral valve tissue (AMVT) is a rare congenital cardiac anomaly that mainly diagnosed in the first decade of life. However, asymptomatic cases may not be diagnosed even up to adulthood.
Mohammad Nasir Hematian, Shirin Torabi, Sedigheh Hantoushzadeh, Alireza Dehestani, Minoo Dadkhah, Reza Shabanian   +5 more
doaj   +1 more source

Symptomatic giant left atrial aneurysm in a child : a rare entity [PDF]

, 2010
Isolated left atrial aneurysms are rare entities in clinical practice. Usually the condition is diagnosed in the second to fourth decades of life. The presence of such lesions in the pediatric age group is scantily described.
Awasthy, Neeraj, Iyer, Killugudi S., Radhakrishnan, Sitaraman, Shrivastava, Sameer, Tomar, Munesh   +4 more
core   +1 more source

Neutrophil–Endothelium Interaction Mediated by S100A9 Promotes Pulmonary Vascular Remodeling During Pulmonary Hypertension

Advanced Science, EarlyView.
This study investigates the critical mechanisms underlying pulmonary hypertension progression, with a focus on the novel role of neutrophil‐derived S100A9 in endothelial dysfunction‐mediated pulmonary vascular remodeling. By integrating human lung samples, multi‐omics analyses, animal models, and mechanistic in vitro studies, it is revealed that how ...
Yu Guo, Zhenqiang Gao, Ruoyang Zhang, Huanyu Long, Muzhi Zhang, Lin Liu, Zhe An, Yuezhe Shi, Ye Cui, Yufeng Jia, Lei Wang, Ying Sun, Jie Liu, Wei Wang   +13 more
wiley   +1 more source

Does Larger Fetal Ascending Aorta Than the Pulmonary Artery Indicate Major Cardiac Anomaly?

Gynecology Obstetrics & Reproductive Medicine, 2021
OBJECTIVE: This study investigated the cases in which the fetal ascending aorta is larger than the main pulmonary artery on the three-vessel view and aimed to determine the relationship between the larger ascending aorta and major cardiac anomalies ...
Safak Yilmaz Baran, Alev Arslan, Gulsen Dogan Durdag, Hakan Kalayci, Seda Yuksel Simsek, Songul Alemdaroglu   +5 more
doaj   +1 more source

Accuracy of pulse oximetry screening for detecting critical congenital heart disease in the newborns in rural hospital of Central India [PDF]

, 2013
Congenital cardiovascular malformations are the most common category of birth defects and responsible for mortality in the first twelve months of life.
Gadekar, A., Japzape, T., Lakhkar, Bhawna, Suwarnakar, K., Taksande, Amar M.   +4 more
core   +1 more source