Results 41 to 50 of about 423,516 (231)

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

Double-chambered left ventricle diagnosis by 2D and 3D echocardiography : From fetus to birth

, 2019
Double-chambered left ventricle (DCLV) is a rare cardiac anomaly and is characterized by the division of the left ventricle by abnormal muscle and/or fiber bundles into two chambers.
Xue, Chao, Han, Jiancheng, Zhang, Ye, Gu, Xiaoyan, Henein, Michael,, He, Yihua, Zhao, Ying   +6 more
core   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Fetal echocardiography in fetal ovarian cysts [PDF]

, 1970
Objectives: The aim of the study was to evaluate the outcome of fetuses with ovarian cysts in relation to fetal echocardiography. Material and methods: In the Department for Diagnosis and Prophylaxis of Birth Defects at the Polish Mother's Memorial ...
Oszukowski, Przemysław, Wilczyński, Jan, Szaflik, Krzysztof, Słodki, Maciej, Janiak, Katarzyna, Respondek-Liberska, Maria, Chilarski, Andrzej   +6 more
core  

EAE/ASE recommendations for the use of echocardiography in new transcatheter interventions for valvular heart disease

, 2011
The introduction of devices for transcatheter aortic valve implantation, mitral repair, and closure of prosthetic paravalvular leaks has led to a greatly expanded armamentarium of catheter-based approaches to patients with regurgitant as well as stenotic
KEANE MG, BUCK T, HAHN RT, SILVESTRY FE, GONÇALVES A, DI BELLO, VITANTONIO, DOCUMENT REVIEWERS EUROPEAN ASSOCIATION OF ECHOCARDIOGRAPHY EAE, NIHOYANNOPOULOS P, VANOVERSCHELDE JL, LA CANNA G, ZAMORANO JL, MONAGHAN MJ, BADANO LP, AMERICAN SOCIETY OF ECHOCARDIOGRAPHY ASE THE ASE GUIDELINES AND STANDARDS COMMITTEE AND THE ASE BOARD OF DIRECTORS, CHAN KL, GILLAM LD, VAHANIAN A, BRUCE C   +17 more
core   +1 more source

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

Advanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang, Mengqi Zeng, Cunxiao Sun, Yuhan Gou, Zhaode Feng, Weiqiang Lv, Chaoying Yan, Hansen Wu, Pengfei Zhang, Jie Xu, Ke Cao, Hao Li, Mingge Ding, Zhongbo Liu, Xing Zhang, Jiankang Liu, Xuan Zou, Zhihui Feng   +17 more
wiley   +1 more source

A Prospective Study of the Use of Fetal Intelligent Navigation Echocardiography (FINE) to Obtain Standard Fetal Echocardiography Views

, 2016
OBJECTIVE: To evaluate the performance of Fetal Intelligent Navigation Echocardiography (FINE) applied to spatiotemporal image correlation (STIC) volume datasets of the normal fetal heart in generating standard fetal echocardiography views ...
Veronese, Paola, Gervasi, Maria Teresa, Maria Teresa Gervasi, Roberto Romero, Paola Veronese, Yeo, Lami, CERUTTI, ALESSIA, Lami Yeo, BOGANA, GIANNA, Alessia Cerutti, Romero, Roberto, Gianna Bogana   +11 more
core   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Fetal echocardiography.

, 1990
Fetal echocardiography has become an essential tool for the thorough evaluation of the fetus at risk for congenital heart disease. This examination is now a part of standard medical practice and should no longer be considered investigational.
Hess, L W, McCaul, J F, Hess, D B, Perry, K G   +3 more
core   +1 more source

Accuracy of Prenatal Diagnosis of Congenital Cardiac Malformations [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective To evaluate the accuracy of the diagnosis of fetal heart diseases obtained through ultrasound examinations performed during the prenatal period compared with the postnatal evaluation.
Diesa Oliveira Pinheiro, Bruna Boff Varisco, Marcelo Brandão da Silva, Rafaela Silva Duarte, Graciele Dequi Deliberali, Carlos Roberto Maia, Mirela Foresti Jiménez, Patrícia El Beitune   +7 more
doaj   +2 more sources