Results 21 to 30 of about 24,245 (208)
4D Fetal Echocardiography [PDF]
, 2012 Congenital heart defects (CHD) are the most frequent malformation in the human fetus and are the leading cause of mortality due to malformations in the first year of life. Despite its clinical importance screening performed by ultrasonographic examination during the second trimester of pregnancy has shown disappointingly low detection rates mainly due ...
RIZZO, GIUSEPPE, ARDUINI, DOMENICO
openaire +3 more sources
Ecotoxicology and Environmental SafetyBackground: The relationships between maternal genetic and environmental exposure and conotruncal heart defects (CTDs) have been extensively investigated.
Yanping Ruan +10 more
doaj +1 more source
Advanced Science, EarlyView.This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang +10 more
wiley +1 more source
ToxicsThe relevance of O3 exposure in critical congenital heart disease (CCHD) remains uncertain and requires further investigation. The present study aims at quantitatively assessing the association between ambient O3 exposure during the early pregnancy ...
Yanping Ruan +4 more
doaj +1 more source
Diagnosis, Treatment and Follow-up of Fetal Cardiac Arrhythmia
Journal of Pediatric Research, 2021 Aim:The importance of managing fetal arrhythmia has increased with advances in fetal echocardiography. We aimed to describe the incidence, types, clinical characteristics, treatments, and follow-ups of patients diagnosed with fetal arrhythmia in our ...
Ayşe Şimşek, Tülay Demircan
doaj +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Advanced Science, EarlyView.Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song +10 more
wiley +1 more source
Case Report: Multimodality imaging of a bronchogenic cyst in the interatrial septum
Frontiers in Cardiovascular MedicineIntracardiac bronchogenic cysts (IBCs) are very rare. To date, only a few cases of IBC have been reported in the literature. We report a case of a bronchogenic cyst that arose from the interatrial septum in a 42-year-old man who presented with symptoms ...
Ma Mingming +4 more
doaj +1 more source
Accuracy of Prenatal Diagnosis of Congenital Cardiac Malformations [PDF]
Revista Brasileira de Ginecologia e ObstetríciaObjective To evaluate the accuracy of the diagnosis of fetal heart diseases obtained through ultrasound examinations performed during the prenatal period compared with the postnatal evaluation.
Diesa Oliveira Pinheiro +7 more
doaj +2 more sources
CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction
Advanced Science, EarlyView.CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma +12 more
wiley +1 more source