Results 111 to 120 of about 245,537 (321)

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia   +7 more
wiley   +1 more source

Unrecognized maternal heart rate artefact in cases of perinatal mortality reported to the United States Food and Drug Administration from 2009 to 2019: a critical patient safety issue

open access: yesBMC Pregnancy and Childbirth, 2019
Background Maternal heart rate artefact is a signal processing error whereby the fetal heart rate is masked by the maternal pulse, potentially leading to danger by failure to recognize an abnormal fetal heart rate or a pre-existing fetal death.
Daniel J. Kiely   +2 more
doaj   +1 more source

3D Bioprinted Head and Neck Squamous Cell Carcinoma (HNSCC) Model Using Tunicate Derived Nanocellulose (NC) Bioink

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A 3D bioprinted HNSCC model for use in anti‐cancer drug testing is established in proof‐of‐concept. The innovative tunicate‐derived nanocellulose hydrogel proved to be a viable alternative to gelatin‐based hydrogel, offering improved bioprintability for HNSCC model establishment.
Alexya Azhakesan   +7 more
wiley   +1 more source

Extract fetal ECG from single-lead abdominal ECG by de-shape short time Fourier transform and nonlocal median [PDF]

open access: yesarXiv, 2016
The multiple fundamental frequency detection problem and the source separation problem from a single-channel signal containing multiple oscillatory components and a nonstationary noise are both challenging tasks. To extract the fetal electrocardiogram (ECG) from a single-lead maternal abdominal ECG, we face both challenges.
arxiv  

Soft Pneumatic Device Designed to Mimic the Periosteal Environment for Regulating the Fate of Mesenchymal Stem Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a custom‐made soft pneumatic device (SPD) that mimics complex mechanical forces and fluid flow to enhance in vitro cell differentiation. It shows that low mechanotransduction promotes MSC differentiation into osteoprogenitor cells, while high mechanotransduction causes structural disruptions and cell detachment, providing new ...
Gwang‐Bum Im   +9 more
wiley   +1 more source

Salt‐Compact Albumin as a New Pure Protein‐based Biomaterials: From Design to In Vivo Studies

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A new class of materials built entirely of native albumin protein is designed using a simple protocol based on salt‐assisted compaction, breaking with current crosslinking strategies. This green process leads, surprisingly, to water‐insoluble handable materials with high preservation of their native protein structures and Young's modulus close to that ...
Eya Aloui   +19 more
wiley   +1 more source

Drugs and the fetal heart rate. [PDF]

open access: bronze, 1971
Jan de Haan, L.A.M. Stolte
openalex   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

open access: yesAdvanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche   +16 more
wiley   +1 more source

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