Results 121 to 130 of about 2,022,294 (304)
Advanced Science, EarlyView.ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang +6 more
wiley +1 more source
Advanced Science, EarlyView.The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo +20 more
wiley +1 more source
Iranian Journal of Public Health, 2014 Most fetal heart rate patterns can be interpreted accurately so that management decisions can be made correctly. How-ever, few fetal heart rate patterns are so ambiguous that the obstetricians cannot interpret them precisely.
Yan-Zhen Zhang +3 more
doaj
The value of 3D and 4D assessments of the fetal heart
, 2014 Edward Araujo Júnior, Liliam Cristine Rolo, Luciane Alves Rocha, Luciano Marcondes Machado Nardozza, Antonio Fernandes MoronDepartment of Obstetrics, Federal University of São Paulo (UNIFESP), São Paulo, BrazilAbstract: The objective
Nardozza LM +4 more
core
Pulse oximetry screening for clinically unrecognized critical congenital heart disease in the newborns [PDF]
, 2007 The aim of this article is to determine the incidence of clinically unrecognized critical congenital heart disease (CCHD) in the newborns by using pulse oximetric screening.peer ...
Pongpanich, Boonchab +2 more
core
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Entropy profiling for detection of fetal arrhythmias in short length fetal heart rate recordings
, 2020 Entropy profiling for detection of fetal arrhythmias in short length fetal heart rate ...
Chandan Karmakar (13063638) +4 more
core
Advanced Science, EarlyView.ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source
, 2004 Chorioamnionitis (CA) is asymptomatic in a large fraction of the cases. Here, we report a case of a 39 weeks' gestation infant, with persistent fetal heart rate hypovariability as the only prenatal clinical sign in histologic ...
LATINI G. +3 more
core +1 more source