Results 111 to 120 of about 1,903,771 (265)

Fetal congenital heart disease and intrauterine growth restriction: a retrospective cohort study

, 2012
Fetal congenital heart disease may lead to abnormal fetal growth. Our objective was to estimate the association between fetal congenital heart disease (CHD) and intrauterine growth restriction (IUGR) in an effort to better inform clinical management of ...
Odibo, Anthony O, Cahill, Alison G, Roehl, Kimberly A, Wallenstein, Matthew B, Longman, Ryan E, Harper, Lorie M, Macones, George A   +6 more
core   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Passive fetal heart rate monitoring apparatus and method with enhanced fetal heart beat discrimination [PDF]

, 1994
An apparatus for acquiring signals emitted by a fetus, identifying fetal heart beats and determining a fetal heart rate is presented. Multiple sensor signals are outputted by a passive fetal heart rate monitoring sensor.
Pretlow, Robert A., III, Zahorian, Stephen A., Livingston, David L.   +2 more
core  

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

Advanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang, Yuqing Yuan, Wei Shen, Xiuxiu Yang, Xiaokang Wu, Haihua Zhou, Yi Hu, Qing Zhu   +7 more
wiley   +1 more source

Position paper on physical activity for children and young people

, 2001
The National Heart Alliance is an independent non-governmental organisation which aims to increase co-operation among organisations involved in the fight against heart disease. ➢ The National Heart Alliance includes representation from a wide range of
National Heart Alliance
core  

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Passive fetal heart rate monitoring apparatus and method with enhanced fetal heart beat discrimination [PDF]

, 1996
An apparatus for acquiring signals emitted by a fetus, identifying fetal heart beats and determining a fetal heart rate. Multiple sensor signals are outputted by a passive fetal heart rate monitoring sensor.
Zahorian, Stephen A., Pretlow, III, Robert A., Livingston, David L.   +2 more
core  

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Fetal MRI : an essential step in interpreting complex ultrasound findings [PDF]

, 2016
Background: Fetal magnetic resonance imaging (MRI) allows for the interpretation of complex fetal anomalies detected on ultrasound (US). Locally it has been available since 2013 but has remained underused.
Gatt, Andre Stefan, Baldacchino, Ian, Saliba, Isabelle   +2 more
core  

High‐sensitivity CRP is elevated in pregnant women with overweight and obesity and modulated by gestational weight gain

Acta Obstetricia et Gynecologica Scandinavica
Introduction The global obesity epidemic presents a growing challenge in perinatal medicine and obstetrics, as it is associated with a higher risk of adverse maternal and perinatal outcomes.
Ann‐Christin Tallarek, Tanja Zeller, Alina Goßling, Caroline Kellner, Gudula Hansen, Mirja Pagenkemper, Charlotte Humke, Evelyn Annegret Huhn, Christopher Urbschat, Petra Clara Arck, Anke Diemert   +10 more
doaj   +1 more source