Results 51 to 60 of about 263,321 (360)

Accurate Fetal QRS-Complex Classification from Abdominal Electrocardiogram Using Deep Learning

International Journal of Computational Intelligence Systems, 2023
Fetal heart monitoring during pregnancy plays a critical role in diagnosing congenital heart disease (CHD). A noninvasive fetal electrocardiogram (fECG) provides additional clinical information for fetal heart monitoring.
Annisa Darmawahyuni, Bambang Tutuko, Siti Nurmaini, Muhammad Naufal Rachmatullah, Muhammad Ardiansyah, Firdaus Firdaus, Ade Iriani Sapitri, Anggun Islami   +7 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Normal fetal echocardiography ratios - a multicenter cross-sectional retrospective study

Journal of Perinatal Medicine
Normal fetal echocardiography ratios reflect blood flow balance and developmental patterns, providing a basis for more accurate diagnosis and prediction of congenital heart disease in fetuses.
Xie Jiaoyang, Weng Zongjie, Yang Tingyang, Wu Hanbin, Peng Ni, Wang Hairui, Zhang Ye, Han Jiancheng, Ji Xueqin, Liu Xiaoli, Zhang Lixin, He Yihua, Gu Xiaoyan   +12 more
doaj   +1 more source

A journey from adult to fetal echocardiography

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2018
As a cardiologist in a group practice or hospital settings, many a times you are requested to comment on fetal Echocardiography performed by radiologist or fetal medicine specialist.
U P Singh, Hargunbir Singh, Ladbans Kaur
doaj   +1 more source

Non-invasive Fetal Electrocardiography for Intrapartum Cardiotocography

Frontiers in Pediatrics, 2020
Fetal monitoring is important to diagnose complications that can occur during pregnancy. If detected timely, these complications might be resolved before they lead to irreversible damage.
Rik Vullings, Rik Vullings, Judith O. E. H. van Laar   +2 more
doaj   +1 more source

Significance of Atrial and Brain Natriuretic Peptide Measurements in Fetuses With Heart Failure

Frontiers in Physiology, 2021
Fetal heart failure is mainly caused by congenital heart defect and arrhythmia. It is difficult to appropriately diagnose the severity of fetal heart failure simply by ultrasonography because the development of a fetal heart in fetoplacental circulation ...
Takekazu Miyoshi, Takekazu Miyoshi, Hiroshi Hosoda, Naoto Minamino   +3 more
doaj   +1 more source

Color and power Doppler combined with Fetal Intelligent Navigation Echocardiography (FINE) to evaluate the fetal heart

Ultrasound in Obstetrics and Gynecology, 2017
To evaluate the performance of color and bidirectional power Doppler ultrasound combined with Fetal Intelligent Navigation Echocardiography (FINE) in examining the fetal heart.
Lami Yeo, Lami Yeo, Lami Yeo, R. Romero
semanticscholar   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source