Results 41 to 50 of about 2,022,294 (304)

Rare damaging variants in the sex differences of congenital heart disease: an exome sequencing studyResearch in context

EBioMedicine
Summary: Background: Congenital heart disease (CHD) exhibits a marked male predominance in birth prevalence, yet the genetic mechanisms underlying this sex disparity remain poorly understood.
Hairui Sun, Xiaoyan Hao, Hankui Liu, Siyao Zhang, Jiancheng Han, Ye Zhang, Tingting Liu, Xian Yang, Hairui Wang, Jiaqi Fan, Yuxuan Guan, Ni Peng, Jiaoyang Xie, Hongmei Xia, Xueqin Ji, Yan Xu, Jianguo Zhang, Jianbin Wang, Feng Lan, Hongjia Zhang, Xiaoyan Gu, Yihua He   +21 more
doaj   +1 more source

Mathematical tools for identifying the fetal response to physical exercise during pregnancy [PDF]

, 2008
In the applied mathematics literature there exist a significant number of tools that can reveal the interaction between mother and fetus during rest and also during and after exercise.
Stirling, James, Barakat Carballo, Rubén O., Stirling, James R., Zakynthinaki, María S., Barakat Carballo, Ruben   +4 more
core  

Recognition of Normal Fetal Cardiac Structures

, 2016
Fetal heart examination requires in depth knowledge of fetal cardiac physiology and fetal cardiac anatomy. Therefore, the cardiac sonographer must possess considerable skills to acquire optimum images on cardiac anatomy on predefined standard views.
Balci, Burcin Karamustafaoglu, Uzun, Orhan, Orhan Uzun, Goynumer, Gokhan, Burçin Karamustafaoğlu Balcı, Gokhan Goynumer   +5 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Magnesium sulfate-induced blocked premature atrial contractions resulting in fetal bradyarrhythmia

Journal of Arrhythmia, 2014
Here, we present a rare case of fetal bradyarrhythmia following magnesium sulfate therapy for preterm labor. After we switched treatment from ritodrine hydrochloride to magnesium sulfate at 25 weeks' gestation, the fetal heart rate dropped from 150 bpm ...
Takekazu Miyoshi, MD, Wataru Shimizu, MD, Takashi Noda, MD, Yoshinari Kobayashi, MD, Chizuko A. Kamiya, MD, Kaoru Yamanaka, MD, Reiko Neki, MD, Jun Yoshimatsu, MD, Shiro Kamakura, MD   +8 more
doaj   +1 more source

The Fetal Heart [PDF]

Journal of Diagnostic Medical Sonography, 1986
The purpose of this article is to inform the sonographer about how to evaluate the normal fetal heart during routine obstetric examinations. With basic knowledge of how the fetal heart should appear, a sonographer can perform an adequate basic examination in a short period of time, depending on experience. The ventricles, atria, atrioventricular valves,
openaire   +1 more source

A review of congenital heart block [PDF]

, 2003
Congenital heart block is a rare disorder. It has an incidence of about 1 in 22,000 live births. It may be associated with high mortality and morbidity.
Glickstein, J., Buyon, Jill P., Friedman, Deborah M., Duncanson, L.J.   +3 more
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Correlation between tricuspid regurgitation and fetal cardiac structure or signs and prenatal genetic testing abnormalities in fetuses at 12+ 0 to 16+ 0 weeks of gestation

BMC Pregnancy and Childbirth
Objective This study aimed to investigate the correlation between tricuspid regurgitation (TR) in fetuses at 12+ 0 to 16+ 0 weeks of gestation and fetal cardiac structure, signs, and prenatal genetic testing abnormalities.
Zheng Shuai, Wang Jingyi, Sun Hairui, Han Jiancheng, Guan Yuxuan, Wang Hairui, Zhou Xiuyun, He Yihua   +7 more
doaj   +1 more source

Case Report: De novo USP9X missense mutation in a male fetus with pulmonary atresia and ventricular septal defect: expanding the genotype-phenotype spectrum of USP9X-related disorders

Frontiers in Cardiovascular Medicine
BackgroundPathogenic variants in the X-linked USP9X gene, which evades X-chromosome inactivation, have been predominantly linked to neurodevelopmental disorders (NDDs). Accumulating evidence has linked USP9X dysfunction to congenital heart disease (CHD),
Tingting Man, Tingting Man, Hairui Sun, Hairui Sun, Xiaoyan Hao, Xiaoyan Hao, Xiaowei Liu, Xiaowei Liu, Yihua He, Yihua He, Yihua He   +10 more
doaj   +1 more source