Results 51 to 60 of about 491,106 (310)
BackgroundThe NONO gene is located on chromosome Xq13.1 and encodes a nuclear protein involved in RNA synthesis, transcriptional regulation, and DNA repair.
Hairui Sun +15 more
doaj +1 more source
Mathematical tools for identifying the fetal response to physical exercise during pregnancy [PDF]
In the applied mathematics literature there exist a significant number of tools that can reveal the interaction between mother and fetus during rest and also during and after exercise.
Barakat Carballo, Ruben +2 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Conclusions: This study broadens the spectrum of variants of TSC1 and TSC2 genes, reaffirming the clinical diagnosis of patients through genetic testing.
Jian Chen +11 more
doaj +1 more source
Fetal cardiac interventions: clinical and experimental research
Fetal cardiac interventions for congenital heart diseases may alleviate heart dysfunction, prevent them evolving into hypoplastic left heart syndrome, achieve biventricular outcome and improve fetal survival.
Shi-Min Yuan, Gulimila Humuruola
doaj +1 more source
Accurate Fetal QRS-Complex Classification from Abdominal Electrocardiogram Using Deep Learning
Fetal heart monitoring during pregnancy plays a critical role in diagnosing congenital heart disease (CHD). A noninvasive fetal electrocardiogram (fECG) provides additional clinical information for fetal heart monitoring.
Annisa Darmawahyuni +7 more
doaj +1 more source
Passive fetal heart rate monitoring apparatus and method with enhanced fetal heart beat discrimination [PDF]
An apparatus for acquiring signals emitted by a fetus, identifying fetal heart beats and determining a fetal heart rate. Multiple sensor signals are outputted by a passive fetal heart rate monitoring sensor.
Livingston, David L. +2 more
core +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Prenatally diagnosed fetal heart rhythm abnormalities—incidence, diagnosis and outcome
Backrounds: Fetal arrhythmias represent a significant cause of fetal morbidity and mortality and occur in approximately 1–3% of pregnancies. The unknown fetal arrhythmias are the cause of intrauterine fetal demise in as many as 3–10% of cases, as well as
Jelena Stamenković +7 more
doaj +1 more source
Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease. [PDF]
How stage-specific enhancer dynamics modulate gene expression patterns essential for organ development, homeostasis and disease is not well understood.
Akiyama, Jennifer A +8 more
core +2 more sources

