Results 61 to 70 of about 2,022,294 (304)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Fetal cardiac interventions: clinical and experimental research

Advances in Interventional Cardiology, 2016
Fetal cardiac interventions for congenital heart diseases may alleviate heart dysfunction, prevent them evolving into hypoplastic left heart syndrome, achieve biventricular outcome and improve fetal survival.
Shi-Min Yuan, Gulimila Humuruola
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Normal fetal echocardiography ratios - a multicenter cross-sectional retrospective study

Journal of Perinatal Medicine
Normal fetal echocardiography ratios reflect blood flow balance and developmental patterns, providing a basis for more accurate diagnosis and prediction of congenital heart disease in fetuses.
Xie Jiaoyang, Weng Zongjie, Yang Tingyang, Wu Hanbin, Peng Ni, Wang Hairui, Zhang Ye, Han Jiancheng, Ji Xueqin, Liu Xiaoli, Zhang Lixin, He Yihua, Gu Xiaoyan   +12 more
doaj   +1 more source

Generation of a TSC2 knockout embryonic stem cell line by CRISPR/Cas9 editing

Stem Cell Research
Tuberous Sclerosis Complex (TSC) is a severe developmental disorder with various clinical effects, primarily caused by TSC2 gene mutations, often involving loss of function(Henske,et al., 2016).To explore role of TSC2 in human heart development, we ...
Siyao Zhang, Jiaqi Fan, Hairui Sun, Xiaoyan Hao, Yihua He   +4 more
doaj   +1 more source

Accurate Fetal QRS-Complex Classification from Abdominal Electrocardiogram Using Deep Learning

International Journal of Computational Intelligence Systems, 2023
Fetal heart monitoring during pregnancy plays a critical role in diagnosing congenital heart disease (CHD). A noninvasive fetal electrocardiogram (fECG) provides additional clinical information for fetal heart monitoring.
Annisa Darmawahyuni, Bambang Tutuko, Siti Nurmaini, Muhammad Naufal Rachmatullah, Muhammad Ardiansyah, Firdaus Firdaus, Ade Iriani Sapitri, Anggun Islami   +7 more
doaj   +1 more source

Comparing accuracy of obstetric sonography and fetal echocardiography during paediatric cardiology consultation in prenatal diagnosis of congenital heart disease [PDF]

, 2015
OBJECTIVE: Compare the diagnostic accuracy of fetal echocardiogram performed by obstetrician alone and that performed jointly by obstetrician and paediatric cardiologist for congenital heart disease. METHOD: All cases of suspected fetal congenital heart
Lai, WSC, Lee, CP, Chau, AKT
core  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

A journey from adult to fetal echocardiography

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2018
As a cardiologist in a group practice or hospital settings, many a times you are requested to comment on fetal Echocardiography performed by radiologist or fetal medicine specialist.
U P Singh, Hargunbir Singh, Ladbans Kaur
doaj   +1 more source