Results 81 to 90 of about 6,649,528 (303)
Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility
Advanced Healthcare Materials, EarlyView.A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji +10 morewiley +1 more sourceHeart disease in infants of diabetic mothers [PDF]
, 2000 Congenital anomalies occur more commonly in infants born to diabetic
mothers, and cardiac defects predominate. Although respiratory problems are
also frequently found in those infants, they need to be differentiated from
cardiovascular problems that ...Narchi, Hassib, Kulaylat, N.core Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes
Advanced Healthcare Materials, EarlyView.Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng +13 morewiley +1 more sourceFetal growth, early life circumstances, and risk of suicide in late adulthood.
, 2011 Recent studies in Sweden and Scotland have found early life conditions to be associated with increased risk of attempted and completed suicide in adolescence and young adulthood. It is not known, however, whether early life conditions affect suicide risk Danziger, Phoebe Day, Silverwood, Richard, Koupil, Ilona, Danziger, P. D., Richard Silverwood, Ilona Koupil, Koupil, Ilona,, Phoebe Day Danziger, Silverwood, R. +8 morecore +1 more sourceIdentification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders [PDF]
, 2011 Elevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 individuals, we identified 14 new loci associated with heart rate and ...Kooner, A.S., Cusi, D., Munroe, P., Laiho, Päivi, P. Elliott, D. Absher, Assimes, Themistocles L., Ingelsson, E., C. Wijmenga, Sibon, O.C., Sanna, Serena, Rossin EJ, Pfeufer, Arne, Anneli Pouta, van der Schouw, Y.T., Qi, L., Knowles, JW, Hicks, Andrew A, D. J. Hunter, Groop L, van der Klauw, MM (Melanie), Nelis, M, Albert, Christine M., Olsen, J.V., Sibon, Ody C M, Mari Nelis, Chip Stewart, Toshiko Tanaka, Kim, Young Jin, Peters, Annette, van Gilst, W., Whitfield, J., A. U. Jackson, Kim, Y. J., Poulter, Neil R, Smith, AV, Holewijn, S, Steven A McCarroll, Arnar, D.O., Kathryn A Miller, McArdle WL, Scott RA, D. O. Arnar, Navarro, Pau, M. R. Markus, Antti Jula, Qi, Lu, Qi L, Uitterlinden, André G, Tarasov, K., Forouhi, Nita G., O'Donnell, C., W. L. Caulfield, Jarvelin, M., Stefansson, K, Chambers, John C, Whitfield, JB, Smith AV, O'Donnell, CJ, M. den Heijer, Waite L, Gary Curhan, Robert A Scott, K. L. Lunetta, Montgomery, G.W., Igl, W., Draisma HH, Sever, Peter S, Knowles, J., Tarasov, KV, Quertermous, T., Heckbert, Susan R., J. C. Bis N. Bouatia Naji, Hsueh, Wen-Chi, Milani, L., Hingorani A, Munroe, PB, de Geus, E.J., de Bakker, Paul I. W., M. Chung, Handsaker, Robert E, Qi, L, Thompson, J., de Geus, Eco J C, Eijgelsheim, Mark, Smith, GD, Evans DM, Handsaker, Robert E., S. H. Wild, Claude Bouchard, Strachan, David P., Ong, KK, Smith, G., Dan E Arking, Johnson, T, Jordan T Shin, M. Kumari, Jula A, Shuldiner AR, Femke Hoogstra-Berends, Jarvelin MR, Xie, W.J., Alonso, Alvaro, Kerr, KF, R. N. Luben, Peter S Chines, et al., Joshua W Knowles, van Gilst, WH, Quertermous T, Peal, D.S., Ketkar S, Rizzi F, Olsen, Jesper V., Nieminen MS, de Boer, Rudolf A., Loic Yengo, Johnson T, Y. T. van der Schouw, Zhang, W., P. Navarro, Raitakari, Olli T., Vitart, Veronique, van der Schouw, Y., Westra, HJ, Iribarren, Carlos, Ody C M Sibon, Laiho, Paeivi, Martin, Nicholas G, A. Johansson, Jolanda M A Boer, Kähönen, M., C. Langenberg, Ketkar, S, Iacoviello, Licia, Neil R Poulter, van der Schouw, YT, Hadley, D., Evelin Mihailov, Montasser ME, E. J. de Geus, Thompson, JR, Pourcain, Beate St., Westra, H., B. St Pourcain, Ong, K.K., Gudbjartsson, Daniel, Weedon, Michael N., Wareham, N.J., N. C. Onland Moret, Scott, Robert A., Barlassina C, Ulf Gyllensten, van der Schouw YT, Visscher, P., Pourcain, BS, Loos R.J., E. B. Rimm, Erdmann, Jeanette, Tardif JC, Salo, P, Alonso A, van Veldhuisen DJ, B. A. Oostra, E. Widen, Pedersen, Nancy L., Tim D Spector, Verschuren, W. M. Monique, van Gilst, Wiek H, Zhang, WH, Laiho, P, Willer, Cristen, Pedersen, Nancy L, Visscher, PM, Brage, S., Hicks, Andrew A., Lynch SN, Cornelis MC, Verschuren, W.M.M., Rankinen, T, Jackson, A.U., Sever, P.S., Annette Peters, Wilson, James F, Huikuri, Heikki V, den Hoed, M, Kemp, J.P., Rankinen T, Iacoviello, L, S. Bandinelli, Hofman A, Federica Rizzi, Mateo Leach I, de Geus, EJC, Daniel Gudbjartsson, Erdmann, J, Leusink M, Hottenga, J.J., Peter M Visscher, Albert V Smith, Hicks, A.A., Beckmann, Jacques S, Weedon MN, Alvaro Alonso, H. J. Westra, Polasek, Ozren, Brage, S, Thorsteinsdottir, U, Ruth J F Loos, Jarvelin, MR, Elliott P, Miller, Kathryn A., van Duijn, Cornelia M., W. C. Hsueh, Sehmi, J.S., Müller-Nurasyid, M., Lakatta, Edward G., Shields DC, Medland, S.E., Virtamo J, Jackson, Anne U, Newton-Cheh, C, Snieder, Harold, A. S. Havulinna, Huikuri HV, Elizabeth J Rossin, Tuomilehto J, Zhao, JH, D. Kuh, Kivimaki, M., Tardif, J.C., Yang, L., Pramstaller, PP, O'Reilly PF, Mihailov E, Tarasov, Kirill V, Smith, A., Vollenweider, P, Wilmar Igl, Knowles JW, Tarasov, K.V., Marcello R P Markus, Brundel, Bianca J J M, Stolk, Ronald P, Singleton AB, Nolte, I., Visscher, Peter M., Rao DC, Elisabeth Widen, Elliott, P., Fuchsberger, C., M. Dörr, L. Qi, Pramstaller, P., Cornelis, Marilyn C, Salo, P., Zhao, J., Rankinen, Tuomo, Kim, YJ, Tanaka, T, Marjo-Riitta Jarvelin, Handsaker, R.E., Lakatta, E., Jamshidi, Yalda, Psaty, Bruce M., Lynch, S.N., Wong, QN, Khaw, K., Jan A Kors, Kiemeney, L.A.L.M., Mihailov, Evelin, Mitchell, Braxton D., T. Rankinen, Tuomilehto, J., Sarah E Medland, N. J. Timpson, U. Thorsteinsdottir, Morrison, Alanna C, Pedro Marques-Vidal, Milan, David J, Kim, Y., Dirk J van Veldhuisen, Serena Sanna, Lakatta, EG, Holm H, P. A. Lind, E. Ingelsson, Caulfield, W., Shin, Jordan T., CHARGE AF Consortium, den Hoed M, M. E. Montasser, Anne B Newman, Richard A Kronmal, Timpson NJ, Markus, M., Hartikainen, A., Dorret I Boomsma, Segrè AV, Bochud, M., W. Wheeler, Wheeler, W., Wong, Q., Kari Stefansson, Bis JC, Khaw, KT, Hartikainen, AL, Rimm, Eric B, Peal DS, Hu, Frank B., Jensen, MK, Rotter JI, Mihailov, E., Chines, Peter S., Pedersen, N., St Pourcain, Beate, Poulter, N.R., Smith, G.D., Fischer, K (Kirsten), Absher D, Vilmundur Gudnason, Rao, Dabeeru C., Thompson, J.R., Jensen, M., Medland, Sarah E., Felix, Stephan B, Bis, J.C., Wilson, J.F., Samani, N.J., Kronmal, Richard A, Gerjan Navis, T. Johnson, Raitakari, O., Pedersen, NL, van Duijn CM, D. Gudbjartsson, Samani NJ, Olli T Raitakari, Soranzo, N., E. Mihailov, Waeber, G., Zoltán Kutalik, Pouta, A., Widen, Elisabeth, Wong, Q.N., Stacey N Lynch, Montasser, ME, Raitakari, OT, Shin JT, Feitosa MF, Isaacs, A., Hunter DJ, S. Padmanabhan, Segrè, A.V., Kiemeney, L.A., St. Pourcain, B., Hwang, S.J., Global BPgen Consortium, Wilson, James F; id_orcid, O'Reilly, P.F., Gabrielle Boucher, Kooner JS, Montasser, M., Navarro P, Lokki, M.L.L., Kuh, D, Young Jin Kim, Ring, S., J. Virtamo, Jerome I Rotter, Brundel, B.J., Morrison AC, Lakatta, Edward G, de Geus, E.J.C., Willemsen, G.; id_orcid, A. Alonso, Rimm, E., Chambers, J.C., Khaw, Kay-Tee, Sever, P., Navarro, P., Montgomery, Grant W, Stricker BH, Ring, SM, Hayward C, Forouhi NG, Holm, H, van der Schouw, Yvonne T., Hoed, M. den, Samani, Nilesh J, Gudbjartsson, D, Kristiansson, Kati, P. M. Visscher, Boomsma, Dorret I., J. S. Sehmi, McArdle, W.L., Sever, PS, A. G. Uitterlinden, Hsueh, W.C., Handsaker, R., Fischer K, Ladenvall C, Michael N Weedon, Hayward, Caroline, Lynch, SN, Lehtimäki T, Kerr, K., Erdmann J, Albert Hofman, Salo P, Igl, Wilmar, Yang, Jiaqi, Scott, R., Boucher, G, T. Esko, Arnar, DO, CARDIoGRAM Consortium, Lynch, S., Handsaker, RE, Scott, RA, Lindsay Waite, Hicks, A., van Veldhuisen, D.J., Müller-Nurasyid, Martina, Rimm, EB, David M Evans, Albanes D, Boucher G, Arnar, D., Kooner, JS, J. A. Kors, Kiemeney, Lambertus A, K. Fischer, Hicks AA, Hicks, AA, Franke, L., Junttila J, Lakatta, E.G., Cusi, D, Weedon, MN, Stanton, A.V., Oostra, B.A., M. M. van der Klauw, A. C. Morrison, Patrick T Ellinor, L. Groop, Pourcain, B. St, Jamshidi Y, Harmen H M Draisma, Yang J, Sibon, Ody C. M.; id_orcid, Graaf, J. de, Michael Boehnke, Westra, H.J., Spector, T.D., Loos, R.J.F., Forouhi, N., G. W. Montgomery, Lynch, Stacey N, Dina, Christian, Wilson, JF, Forouhi, NG, Waeber, G, Jesper V Olsen, Waite, Lindsay, Bouchard, C, de Geus, Eco J. C., Holm, H., Kim, Y.J., Wilson, J., I. B. Borecki, Dawood Darbar, Absher, D., Sehmi, Jaban S., A. B. Newman, Sandosh Padmanabhan, Leif Groop, Weedon, M., Shields, DC, Froguel, P., K. A. Miller, Braxton D Mitchell, Smith GD, David S Peal, Timpson, N.J., Ulf Ekelund, de Bakker, P., Kooner AS, Shields, D., A. Isaacs, Froguel, P, Lynch, Stacey N., Hoogstra-Berends, F., V. Gudnason, Harris, Tamara B, Mark Walker, Boer, J.M.A., Robert E Handsaker, Claes Ladenvall, Boehnke, M, Groop, L, Sanna, S, Isomaa, B., Walker M, de Bakker, P.I.W., Nolte IM, de Geus EJ, Kemp, John P, Newman, Anne B, Raitakari OT, Paul I W de Bakker, Hu, F.B., Hottenga, J.-J., Ellinor, Patrick T., Langenberg, C, Borecki, Ingrid B., Evans, D., M. N. Weedon, Bochud, Murielle, Marques-Vidal, P, Huikuri, HV, Leusink, Maarten, Albert, C.M., Lind, Lars, Sehmi, Jaban S, A. L. Hartikainen, Stefan Kääb, Hoogstra-Berends, Femke, Lunetta, Kathryn L., Milan, David J., Navarro, P, Peal, David S, Evans, DM, Heckbert, Susan R, Tamara B Harris, Ronald P Stolk, Eriksson, Johan, J. Junttila, F. B. Hu FB, Kanon, B, Chanock, Stephen J, Gérard Waeber, Huikuri, H., Wong, A., Wen-Chi Hsueh, Yengo, L., Isomaa, B, Lundby, A., Chines, P.S., Zhang, W.H., Medland SE, John D Rioux, Vandenput, Liesbeth, D. J. van Veldhuisen, I. Rudan, Melanie M van der Klauw, Jarvelin, M.R., Jensen MK, Draisma, H., Stolk, RP (Ronald), Havulinna, A.S., Nolte, IM (Ilja), Martin, NG, J. P. Kemp, S. N. Lynch, Johnson, T., van Duijn, C., Salomaa, V, Jian Yang, Yang, Jian, J. R. O'Connell, Y. Liu, Kanon B, Martin, N., J. T. Shin, Shuldiner, A.R., Padmanabhan S, Jaspal S Kooner, Liu Y, Sharp, S., Sharp S, Hsueh WC, C. M. Albert, Nicola Glorioso, Ring, Susan M, Marja-Liisa L Lokki, Milan, D.J., Isomaa, Bo, Caulfield, W.L., O'Donnell CJ, Snieder, H, Peter S Sever, Nieminen, Markku S, B. Kanon, M. J. Go, Hunter, David J, Päivi Laiho, W. Igl, Hsueh, W.-C., Chines, Peter S, Ellinor, Patrick T, Esko, T, Rotter, Jerome I, Nicholas J Wareham, Claudia Langenberg, Ekelund, U., Whitfield, John B, Kuh, D., Montasser, M.E., Kors, Jan A, Stewart C, Spector, T., Benaglio, Paola, Thompson, John R., Kerr, Kathleen F., Lundby A, Visscher PM, de Boer, R.A., P. Zitting, Erdmann, J., M. Nelis, Rioux, John D, P. I. de Bakker, Laiho P, A. A. Hicks, Bouchard, C., Paavo Zitting, Absher, Devin, Forouhi, Nita G, Dina C, van der Harst, Pim, S. M. Ring, Luigi Ferrucci, Leach, IM, Zitting P, de Boer, RA, Alicia Lundby, Olsen, J., Mika Kähönen, de Boer, R., Fuchsberger, Christian, Peal, D., Njajou, Omer T., Mihailov, E, Pim van der Harst, Heckbert SR, D. C. Rao, Beckmann, J.S., Bruce M Psaty, Olsen, JV, Lokki, Marja-Liisa L, Chambers, John C., Jula, A, Nita G Forouhi, Jamshidi, Y., Strachan, D., Ekelund, U, Waeber, Gerard, Polasek, O., A. Hofman, Ong, Ken K., Uitterlinden, A., Scott, R.A., Chanock, S., Kooner, Angrad S, Sinisalo, Juha, A. S. Kooner, Fischer, Krista, Harris, TB, Søren Brage, Jacqueline de Graaf, Lind, L, Harris, T., Wareham, Nicholas J., O'Connell, J.R., Chanock, SJ, QT-IGCGC Consortium, Arking, Dan E., Lokki, Marja-Liisa L., J. Eriksson, Marcel den Hoed, Draisma, H.H., Draisma, Harmen H. M., Kemp, J., Go, Min Jin, Kääb, Stefan, Timpson, Nicholas J., Zhao, J.H., Singleton, A.B., Ekelund U, Yongmei Liu, S. Ketkar, K. Kristiansson, Maarten Leusink, Miller KA, Verschuren, W., Vitart, V, Bouatia-Naji, N, Rossin, E.J., N. Glorioso, Fuchsberger C, M. Lorentzon, Evans, David M., Hayward, C, Pramstaller PP, Kemp, JP, Assimes, Themistocles L, Jensen, M.K., van der Harst P, Strachan, DP, Whitfield, J.B., Luben, Robert N., Assimes, TL, Themistocles L Assimes, Assimes, T., Spector, TD, CHARGE-AF Consortium, Igor Rudan, J. C. Tardif, Kumari M, W. L. McArdle, Darbar D, Kronmal RA, Lunetta KL, Nieminen, M.S., Ferrucci, L., Glorioso, N., Hartikainen, A.L., Jouke-Jan Hottenga, Holewijn S, Kronmal, RA, Esko T, Leach, I.M., Müller Nurasyid M, Shin, J., Strachan, David P, R. A. de Boer, Kronmal, R., Lakatta EG, Stanton, Alice V., Samani, Nilesh J., Cisca Wijmenga, Bouatia-Naji, Nabila, Virtamo, J, PR GWGWAS Consortium, Hofman, Bert, Hartikainen AL, Langenberg, Claudia, Markus, M.R.P., Hwang SJ, Olsen JV, Brundel, Bianca J. J. M., Marques-Vidal, Pedro, van Veldhuisen, Dirk J., Widen E, Ferrucci, Luigi, Sibon, O.C.M., W M Monique Verschuren, Jaban S Sehmi, Kirill V Tarasov, Feitosa, Mary F., Markus, M.R., Spector, Tim D., Jorma Viikari, Witteman JC, Snieder, H., Yengo L, Havulinna AS, Fuchsberger, C, S. A. McCarroll, Kay-Tee Khaw, Uitterlinden, André, S. E. Medland, Pouta, Anneli, Medland, Sarah E, Kraft, P, Rizzi, F., Lorentzon, Mattias, Pouta A, Sharp, Stephen, Khaw, K.-T., Sanna S, Stolk, Ronald P., Iribarren, C, Chambers, J., Almgren P, Marques Vidal P, Johansson, A, Chanock SJ, J. Yang, O'Donnell, Christopher J., Willemsen G, Mark Eijgelsheim, Havulinna, Aki S, K. K. Ong, Patricia B Munroe, Goyette, P, Chambers, JC, Peal, DS, Nona Sotoodehnia, R. A. Kronmal, Verschuren WM, de Geus, E.J.C.; id_orcid, B. Isomaa, Lokki, M.L., Albert, C., Hadley, D, Wild, S.H., Lunetta, K.L., Gonneke Willemsen, Isomaa B, Brundel, B.J.J.M., Stricker, B.H., Marques-Vidal, P., James F Wilson, Denis C Shields, Barlassina, Cristina, Stefansson, K., Forouhi, N.G., Albert, CM, Markku S Nieminen, Metspalu A, Cho, Yoon Shin, A. V. Segrè, Caroline Hayward, Willemsen, G, Harris, Tamara B., Hunter, David J., Boomsma, D.I.; id_orcid, Navarro, Pau; id_orcid, Stanton, Alice V, Gudbjartsson, D.F., Boomsma, D., Strachan, D.P., Luben, R., Peter Almgren, Uitterlinden, André; id_orcid, Ben A Oostra, Veronique Vitart, Rudolf A de Boer, Viikari, J, Rudan, Igor, Felix, Stephan B., Beckmann, Jacques S., Smith, George Davey, Luben, RN, Zitting, P., Nancy L Pedersen, Markus MR, Ingrid B Borecki, John B Whitfield, Wijmenga, Cisca, Weedon, Michael N, P. Almgren, Johnson, Toby, Salomaa V, O'Donnell, Christopher J, Rossin, E., Hsueh, WC, J. J. Hottenga, Xie, WJ, André G Uitterlinden, Wheeler W, Arnar, David O., T. Quertermous, Bouchard C, Thorsteinsdottir, U., den Heijer M, Cristina Barlassina, Wiek H van Gilst, Boomsma, DI, Waite, L, Xie, W., C. Dina, Daniele Cusi, Rossin, EJ, Sibon OC, Wong, Quenna, Spector, Tim D, Uitterlinden, A.G., Beckmann JS, K. T. Khaw, Sarah H Wild, Philippe Froguel, Ong, K., PR GWAS Consortium, M. Eijgelsheim, W. Zhang, Peters, A, Montgomery, Grant W., A. Hingorani, Kutalik, Z., Psaty, BM, Kaab, S, Spector TD, Ferrucci L, Feitosa, M.F., Walker, M., Oostra BA, Jaako Tuomilehto, Willemsen, G., Kahonen, M, Andrew B Singleton, Chung, M., Psaty, B.M., Boomsma, D.I., Quertermous, T, Westra, Harm-Jan, Nieminen, Markku S., Sinisalo, J, van der Klauw, Melanie M, Psaty, B., Dina, C, Hwang, S.-J., Kraft P, Grant W Montgomery, Pramstaller, Peter P, Hsueh, W., B. M. Psaty, Wijmenga, Cisca; id_orcid, Rudan, I, Shin, JT, Rudan, D, Vitart, V., Boucher, G., Felix, S.B., Milan DJ, Isaacs A, Junttila, Juhani, Juhani Junttila, Christian Fuchsberger, J. Luan, M. Kähönen, O'Connell, Jeffrey R., Hayward, Caroline; id_orcid, Bruno H Ch Stricker, Verschuren, W M Monique, Jian'an Luan, Heijer, Mariska, Song C, K. W. Knowles, Wendy L McArdle, Polasek, O, Boer, JMA, Wong, Andrew, Angrad S Kooner, Nilesh J Samani, D. Darbar, Ohlsson, Claes, Rizzi, Federica, J. Sinisalo, Milan, D., Stricker, Bruno H. Ch, Boehnke, M., N. G. Martin, Geus, E.J. de, Beckmann, J., U. Ekelund, Philippe Goyette, Jensen, Majken K., Kerr, K.F., Ellinor, P., Snieder, Harold; id_orcid, Shamika Ketkar, Bandinelli, S, Milani L, QRS GWAS Consortium, Sanna, S., J. Viikari, Junttila, J., Uitterlinden, Andre G., O. Polasek, Bianca J J M Brundel, Ketkar, Shamika, Rimm EB, Harm-Jan Westra, Lind, P.A., Song, C., Thorsteinsdottir U, Go, MJ, Sibon, OCM, Groop, L., Ellinor, PT, Sotoodehnia N, Walker, M, Loos, Ruth J F, Khaw KT, Munroe PB, T. Tanaka, Kutalik, Zoltan, Ellinor, P.T., Martin den Heijer, Johansson, Asa, Almgren, P., Timpson, Nicholas J, Hofman, A., Chung M, Lu Qi, Smith, Albert V, Milan, DJ +999 morecore +2 more sourcesTumor‐Targeted Hyaluronic Acid/Tannic Acid‐Engineered Oxygen Nanogenerators With IR780 Payloads Enable Dual‐Mode Glutathione Depletion and Effective Singlet Oxygen Generation for Melanoma Treatment
Advanced Healthcare Materials, EarlyView.A hyaluronic acid/tannic acid‐engineered Prussian blue oxygen nanogenerator loaded with IR780 is developed to enhance melanoma phototherapy. By integrating tumor targeting, oxygen self‐supply, and dual‐mode glutathione depletion, the nanoplatform effectively overcomes hypoxia and antioxidant defenses, potentiating synergistic photothermal/photodynamic ...Chai‐How Hsu, I‐Ju Liu, Hsiang‐Yun Chih, Tsai‐Ching Hsu, Ju‐An Liang, Chia‐Wei Kuo, Bor‐Show Tzang, Wen‐Hsuan Chiang +7 morewiley +1 more sourceEngineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction
Advanced Healthcare Materials, EarlyView.FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs, Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu +11 morewiley +1 more source
