Results 121 to 130 of about 821,341 (299)
Single-cell measurement of red blood cell oxygen affinity [PDF]
Oxygen is transported throughout the body by hemoglobin in red blood cells. While the oxygen affinity of blood is well understood and is routinely assessed in patients by pulse oximetry, variability at the single-cell level has not been previously measured.
arxiv
Background Adults with sickle cell anemia (HbSS) are inconsistently treated with hydroxyurea. Objectives We retrospectively evaluated the effects of elevating fetal hemoglobin with hydroxyurea on organ damage and survival in patients enrolled in our ...
C. Fitzhugh+11 more
semanticscholar +1 more source
The role of cyclic nucleotide on fetal and neonantal erythropoiesis [PDF]
For the purpose to reveal the changes in stimulatory effect of dibutyryl-cyclic- AMP on erythropoiesis during ontogenetic development, the author studied syntheses of DNA, RNA and protein of erythroid cells in fetal liver, neonatal and adult bone marrows
Tada, Hiroshi
core +1 more source
The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]
Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core +1 more source
Objective:To compare fetal hematocrit in different timing of delayed cord clamping and fetomaternal outcome at 48 hours after vaginal births.Materials and Methods: 200 term and preterm vaginal births were recruited by inclusion criteria and ...
Somprattana Mungkornkaew+1 more
doaj +1 more source
HAITCH: A Framework for Distortion and Motion Correction in Fetal Multi-Shell Diffusion-Weighted MRI [PDF]
Diffusion magnetic resonance imaging (dMRI) is pivotal for probing the microstructure of the rapidly-developing fetal brain. However, fetal motion during scans and its interaction with magnetic field inhomogeneities result in artifacts and data scattering across spatial and angular domains.
arxiv +1 more source
Hepatocellular carcinoma and fetal hemoglobin.
An immunological method for human hemoglobin assay was established, using which contents of fetal hemoglobin in the blood of hepatocellular carcinoma patients as well as in the extract of hehatocellular carcinoma tissue were measured. With the hemolysate, 4 out of 7 hepatocellular carcinoma cases showed slight but definite increase, 2 out of 10 in the ...
openaire +3 more sources
In the presence of excess hydrogen peroxide (H2O2), ferrous (Fe+2) human hemoglobin (Hb) (α2β2) undergoes a rapid conversion to a higher oxidation ferryl state (Fe+4) which rapidly autoreduces back to the ferric form (Fe+3) as H2O2 is consumed in the ...
Khuanpiroon Ratanasopa+3 more
semanticscholar +1 more source
Studies on Human γ-globin Gene Regulation: Transcription Factors in a Rubik’s Cube [PDF]
The red blood cell is one of the most important blood cells in the human body. Hemoglobin is the major protein in the red blood cell, and functions as a gas transporter (oxygen and carbon dioxide) to all parts of the body. Changes in the structure or the
Papadopoulos, P. (Petros)
core
Background and Objective: Diabetes mellitus is one of complications that thalassemia major patients face with. Hence, blood glucose monitoring is of vital importance to these patients.
M Kosaryan+4 more
doaj