Results 141 to 150 of about 832,435 (375)

Cálculo do volume de sangue necessário para a correção da anemia fetal em gestantes isoimunizadas Blood volume calculation required for the correction of fetal anemia in pregnant women with alloimmunization

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2008
OBJETIVO: obter uma equação capaz de estimar o volume de concentrado de hemácias a ser infundido para correção da anemia em fetos de gestantes portadoras de isoimunização pelo fator Rh, baseado em parâmetros alcançados durante a cordocentese prévia à ...
Mônica Deolindo Santiago   +5 more
doaj   +1 more source

Glucose‐Responsive PAGR1‐Regulated Skeletal Muscle Gene Program Controls Systemic Glucose Homeostasis and Hepatic Metabolism

open access: yesAdvanced Science, EarlyView.
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding   +19 more
wiley   +1 more source

Importância da avaliação da hemoglobina fetal na clínica da anemia falciforme The importance of the evaluation of fetal hemoglobin in the clinical assessment of sickle cell disease

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2008
A anemia falciforme está entre as doenças genéticas mais comuns e mais estudadas em todo o mundo. Ela é causada por mutação no gene β, produzindo alteração estrutural na molécula da hemoglobina.
Rita de Cassia Mousinho-Ribeiro   +3 more
doaj   +1 more source

Serum level of lactate dehydrogenase, homocystein, hemoglobin and platelet in preeclampsia [PDF]

open access: yes, 2011
Objectives: Pre-eclampsia affects approximately 5-8% of pregnant women. The aim of this study was to compare the serum level of Lactate dehydrogenase (LDH), Homocystein, Hemoglubin and platelet in pregnant women diagnosed as pre-eclampsia and a normal ...
Azarhoosh, R.   +5 more
core  

The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds

open access: yesAdvanced Science, EarlyView.
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong   +27 more
wiley   +1 more source

The Ag-195 (C®G) mutation in hereditary persistence of fetal hemoglobin is not associated with activation of a reporter gene in vitro

open access: yesBrazilian Journal of Medical and Biological Research, 2001
Hereditary persistence of fetal hemoglobin is an uncommon, benign disorder in which the expression of gamma-globin genes persists into adult life. Several point mutations have been associated with the increased gamma-globin gene promoter activity.
Schreiber R.   +5 more
doaj  

The mRNA-Binding Protein IGF2BP1 Restores Fetal Hemoglobin in Cultured Erythroid Cells from Patients with β-Hemoglobin Disorders

open access: yesMolecular Therapy: Methods & Clinical Development, 2020
Sickle cell disease (SCD) and β-thalassemia are caused by structural abnormality or inadequate production of adult hemoglobin (HbA, α2β2), respectively.
Christopher B. Chambers   +9 more
doaj  

Human induced pluripotent stem cells can reach complete terminal maturation: in vivo and in vitro evidence in the erythropoietic differentiation model

open access: yesHaematologica, 2012
Background Human induced pluripotent stem cells offer perspectives for cell therapy and research models for diseases. We applied this approach to the normal and pathological erythroid differentiation model by establishing induced pluripotent stem cells ...
Ladan Kobari   +15 more
doaj   +1 more source

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