Results 141 to 150 of about 821,341 (299)

An Allosteric Model for the Influence of $\text{H}^+$ and $\text{CO}_2$ on Oxygen-Hemoglobin Binding [PDF]

open access: yesarXiv
In the physiology of oxygen-hemoglobin binding, an important role is played by the influence of $\text{H}^+$ and $\text{CO}_2$ on the affinity of hemoglobin for $\text{O}_2$. Here we extend the allosteric model of hemoglobin to include these effects. We assume purely allosteric modulation, i.e., that the modulatory effects of $\text{H}^+$ and $\text{CO}
arxiv  

Optical Marking of Alcohol Induced Hemoglobin Modification [PDF]

open access: yesarXiv, 2007
It has been shown that conformational modifications of Hb induced by ethanol consumption can be visualized in optical spectra studying oxygenation kinetics of hemoglobin or mixing hemoglobin with Cibacron blue dye. Better dye affinity of blood proteins extracted from alcoholised rats with respect to those from non-alcoholised ones confirms that ethanol
arxiv  

Relative Affinity of Human Fetal Hemoglobin for Carbon Monoxide and Oxygen [PDF]

open access: bronze, 1969
Rolf R. Engel   +3 more
openalex   +1 more source

The Fourier Evaluation of Tracings and Acidosis in Labor: the FETAL Technique [PDF]

open access: yesarXiv, 2019
Adequate fetal and neonatal development depend upon the presence of a normal acid-base environment during pregnancy and the smooth transition from intra-uterine to extra-uterine life. Current methods to assess fetal pH and acid-base status are invasive and carry significant maternal and fetal risks.
arxiv  

A Fetal Hemoglobin with Abnormal γ-Polypeptide Chains: Hemoglobin Warren [PDF]

open access: bronze, 1965
T. H. J. Huisman   +3 more
openalex   +1 more source

Serum-free Erythroid Differentiation for Efficient Genetic Modification and High-Level Adult Hemoglobin Production

open access: yesMolecular Therapy: Methods & Clinical Development, 2018
In vitro erythroid differentiation from primary human cells is valuable to develop genetic strategies for hemoglobin disorders. However, current erythroid differentiation methods are encumbered by modest transduction rates and high baseline fetal ...
Naoya Uchida   +6 more
doaj  

Assessing maternal and perinatal complication incidence in pregnant patients with sickle cell disease: a retrospective analysis of transfusion therapy at a tertiary care hospital

open access: yesFrontiers in Hematology
BackgroundPregnant individuals with sickle cell disease (SCD) face high maternal and fetal complication rates. While some studies suggest transfusions may improve outcomes, evidence is limited.
Ram Prakash Thirugnanasambandam   +1 more
doaj   +1 more source

Development of a new staining protocol for the Kleihauer–Betke test to facilitate the reading of difficult cases

open access: yesBMC Pregnancy and Childbirth
Background The Kleihauer–Betke (KB) test allows the detection of fetal red blood cells (containing fetal hemoglobin, HbF) in the maternal blood to identify and quantify potential fetal-maternal hemorrhages.
Adrian Serban   +4 more
doaj   +1 more source

In utero diffusion MRI: challenges, advances, and applications [PDF]

open access: yesarXiv, 2019
In utero diffusion MRI provides unique opportunities to non-invasively study the microstructure of tissue during fetal development. A wide range of developmental processes, such as the growth of white matter tracts in the brain, the maturation of placental villous trees, or the fibres in the fetal heart remain to be studied and understood in detail ...
arxiv  

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