Advanced Science, EarlyView.Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin +18 more
wiley +1 more source
Fetal calf serum contains activities that induce fetal hemoglobin in adult erythroid cell cultures [PDF]
, 1990 Pantelis Constantoulakis +3 more
openalex +1 more source
Defect‐Rich 2D Layered Double Hydroxides Enhance Sonodynamic Antibacterial Therapy
Advanced Science, EarlyView.This study develops defect‐rich ultrathin ZnCuW‐LDH nanosheets (DR‐ZnCuW‐LDH) via acid etching. DR‐ZnCuW‐LDH exhibits fourfold enhanced US‐triggered ROS production due to oxygen defects and electronic modulation, demonstrating potent antibacterial efficacy in vitro/vivo.
Qian Liu +6 more
wiley +1 more source
Fetal hemoglobin in mixed hemopoietic colonies (CFU-GEMM), erythroid bursts (BFU-E) and erythroid colonies (CFU-E): assessment by radioimmune assay and immunofluorescence [PDF]
, 1979 AA Fauser, HA Messner
openalex +1 more source
Rod‐Like PLGA Microrobots with Enhanced Motion and Biodegradation for Magnetic‐Guided Drug Delivery
Advanced Intelligent Systems, EarlyView.This study presents drug‐loaded Poly (lactic‐co‐glycolic acid) (PLGA) microrobots fabricated from an oil‐in‐water (O/W) emulsion of PLGA, Fe3O4 nanoparticles, and Adriamycin (DOX). They are formed by film‐forming and stretching microrobots, and exhibit motion analyzed via video‐snapshots, speed graphs, and shape changes, advancing targeted for drug ...
Junkai Zhang +6 more
wiley +1 more source
A hypothesis about the role of fetal hemoglobin in COVID-19
, 2020 Ehsan Sotoudeh, Houman Sotoudeh
openalex +2 more sources
American Journal of Hematology, EarlyView.A novel erythropoietin (EPO) promoter mutation (c.‐136 G>A) causes autosomal dominant erythrocytosis via non‐renal expression of EPO. ABSTRACT We previously reported a five‐generation kindred with autosomal dominant erythrocytosis associated with a novel germline promoter variant in the erythropoietin (EPO) gene (EPO c.‐136 G>A).
Lucie Lanikova +10 more
wiley +1 more source
New approaches to treating chronic obstructive pulmonary disease with Colla corii asini
Animal Models and Experimental Medicine, EarlyView.Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang +5 more
wiley +1 more source
Sequence variations in the 5' hypersensitive site-2 of the locus control region of beta S chromosomes are associated with different levels of fetal globin in hemoglobin S homozygotes [PDF]
, 1992 C. Öner +6 more
openalex +1 more source