Results 241 to 250 of about 821,341 (299)

Development and IND-enabling studies of a novel Cas9 genome-edited autologous CD34⁺ cell therapy to induce fetal hemoglobin for sickle cell disease. [PDF]

Mol Ther
Katta V, O'Keefe K, Li Y, Mayuranathan T, Lazzarotto CR, Wood RK, Levine RM, Powers A, Mayberry K, Manquen G, Yao Y, Zhang J, Jang Y, Nimmagadda N, Dempsey EA, Lee G, Uchida N, Cheng Y, Fazio F, Lockey T, Meagher M, Sharma A, Tisdale JF, Zhou S, Yen JS, Weiss MJ, Tsai SQ.   +26 more
europepmc   +1 more source

A Rare Case of Multiple Bone Infarctions and Abnormal Pulmonary Function Tests in a Patient With Compound Heterozygous Hemoglobin S and Type 2 Hereditary Persistence of Fetal Hemoglobin. [PDF]

Cureus
Alnaqbi KA.
europepmc   +1 more source

Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch

Cell, 2018
Nan Liu, Victoria V. Hargreaves, Qian Zhu, Jesse V. Kurland, Jiyoung A. Hong, Woojin Kim, F. Sher, Claudio Macias-Treviño, J. Rogers, R. Kurita, Yukio Nakamura, Guocheng Yuan, D. E. Bauer, Jian Xu, M. Bulyk, S. Orkin   +15 more
semanticscholar   +1 more source

Detection of Asymptomatic Sickle Cell Hemoglobin Carriers and Fetal Hemoglobin Regulating Genetic Variants in African Descendants from Oaxaca, Mexico. [PDF]

Anemia
Romero-Tlalolini MLÁ, Aguilar-Ruiz SR, Baltiérrez-Hoyos R, Vargas-Arzola J, Hernández-Osorio LA, Vásquez-Garzón VR, Bernardino-Hernández HU, Torres-Aguilar H.   +7 more
europepmc   +1 more source

Hemoglobin switching's surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin.

Current Opinion in Genetics and Development, 2015
D. E. Bauer, S. Orkin
semanticscholar   +1 more source

A Placenta Derived C-Terminal Fragment of beta-Hemoglobin With Combined Antibacterial and Antiviral Activity

, 2020
Bauer, R., Conzelmann, C., Forssmann, W., Gačanin, J., Gerbl, F., Groß, R., Hagemann, B., Kirchhoff, F., Krüger, F., Mankertz, A., Münch, J., Olari, L., Preising, N., Rodríguez, A., Ruiz-Blanco, Y., Rücker-Braun, E., Sanchez-Garcia, E., Santibanez, S., Sauter, D., Spellerberg, B., Stenger, S., Ständker, L., Walther, P., Weil, T., Wiese, S.   +24 more
core   +1 more source

Simvastatin-Mediated Nrf2 Activation Induces Fetal Hemoglobin and Antioxidant Enzyme Expression to Ameliorate the Phenotype of Sickle Cell Disease. [PDF]

Antioxidants (Basel)
Xi C, Palani C, Takezaki M, Shi H, Horuzsko A, Pace BS, Zhu X.   +6 more
europepmc   +1 more source

Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease

Experimental biology and medicine, 2015
B. Pace, Li Liu, Biaoru Li, Levi H C Makala   +3 more
semanticscholar   +1 more source

Middle cerebral artery peak systolic velocity to predict fetal hemoglobin levels in twin anemia–polycythemia sequence

Ultrasound in Obstetrics and Gynecology, 2015
F. Slaghekke, S. Pasman, M. Veujoz, J. Middeldorp, L. Lewi, R. Devlieger, R. Favre, E. Lopriore, D. Oepkes   +8 more
semanticscholar   +1 more source