Results 271 to 280 of about 834,624 (377)

Diagnostic and prognostic role of thrombospondin‐4 levels in pre‐eclampsia: Association with onset type, severity, and perinatal outcome

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the diagnostic and prognostic significance of maternal serum thrombospondin‐4 (TSP‐4) levels in pre‐eclampsia (PE), including comparisons between early‐ and late‐onset disease and between mild and severe cases, and to examine associations with adverse perinatal outcomes. Methods A prospective study was conducted including
Ruken Dayanan, Dilara Duygulu Bulan, Kadriye Yakut Yucel   +2 more
wiley   +1 more source

Microcytosis Merits Evaluation: A Case Report of Hemoglobin S With Hereditary Persistence of Fetal Hemoglobin (HbS-HPFH Syndrome). [PDF]

Cureus
Daniel CE, Bejjani A.
europepmc   +1 more source

Erythroid lineage chromatin accessibility maps facilitate identification and validation of NFIX as a fetal hemoglobin repressor. [PDF]

Commun Biol, 2023
Chaand M, Fiore C, Johnston B, D'Ippolito A, Moon DH, Carulli JP, Shearstone JR.   +6 more
europepmc   +1 more source

An A gamma type of nondeletional hereditary persistence of fetal hemoglobin with a T----C mutation at position -175 to the cap site of the A gamma globin gene [PDF]

, 1989
T. A. Stoming, GS Stoming, KD Lanclos, YJ Fei, C Altay, F. Kutlar, TH Huisman   +6 more
openalex   +1 more source

RRM2‐targeted nanocarrier enhances radiofrequency ablation efficacy in hepatocellular carcinoma through ferroptosis amplification and immune remodeling

iMeta, EarlyView.
This study proposes an innovative therapeutic approach by combining RRM2 gene knockout with a nanocarrier system, significantly enhancing the efficacy of radiofrequency ablation for hepatocellular carcinoma. The study developed a tumor microenvironment‐responsive nanosystem that achieves synergistic effects through SPIO‐mediated and RRM2 knockout ...
Weiliang Hou, Weifeng Hong, Songhua Cai, Dandan Guo, Zhiping Yan, Jinyu Zhu, Yang Shen, Juncheng Wan, Xudong Qu, Wen Zhang, Runkang Zhao, Zhao Xie, Zhongji Chen, Tong Jiang, Yaling Lin, Wenlong Jia, Ling Wang, Zhao Huang, Xuexin Li, Bufu Tang   +19 more
wiley   +1 more source

Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease. [PDF]

PLoS One
Yang JP, Toughiri R, Gounder AP, Scheibe D, Petrus M, Fink SJ, Vallee S, Kenniston J, Papaioannou N, Langston S, Gavva NR, Horman SR.   +11 more
europepmc   +1 more source

Structural and oxidative investigation of a recombinant high-yielding fetal hemoglobin mutant. [PDF]

Front Mol Biosci, 2023
Kettisen K, Nyblom M, Smeds E, Fago A, Bülow L.   +4 more
europepmc   +1 more source

Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate [PDF]

, 1994
GJ Dover, Saul W. Brusilow, Samuel Charache   +2 more
openalex   +1 more source

Decreased fetal hemoglobin over time among youth with sickle cell disease on hydroxyurea is associated with higher urgent hospital use

Pediatric Blood & Cancer, 2016
N. Green, D. Manwani, Mahvish Qureshi, K. Ireland, Arpan A Sinha, A. Smaldone   +5 more
semanticscholar   +1 more source

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source