Results 271 to 280 of about 821,341 (299)

Oxygen Transport by Fetal Bovine Hemoglobin

Journal of Molecular Biology, 1996
The functional properties of fetal bovine hemoglobin have been studied as a function of temperature, chloride and 2,3-diphosphoglycerate (DPG) concentration. The fetal bovine erythrocyte has six times the concentration of the allosteric modulator DPG compared with the adult cell, and yet the oxygen affinity of the fetal hemoglobin still exceeds that of
Clementi, Maria Elisabetta, Scatena, Roberto, Mordente, Alvaro, Condo', S, Castagnola, Massimo, Giardina, Bruno   +5 more
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The oxygen capacity of fetal hemoglobin

American Journal of Obstetrics and Gynecology, 1964
Abstract The oxygen capacity of fetal blood has been noted to be the same as that of the blood of the human adult. Statistical considerations allow the assumption that the oxygen capacity of fetal hemoglobin is the same as that of the adult hemoglobin as defined by resistance to alkaline denaturation.
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Fetal Hemoglobin Alters Hemoglobin A_1c Measurements

Annals of Internal Medicine, 1991
Excerpt To the editors:The letter of Holt and colleagues (1) emphasizes that diabetic subjects with hemoglobin S or C traits will have a falsely low hemoglobin A1cvalue if measured by certain metho...
Richard W. Bergstrom, W. Kenneth Ward, James R. Kelley   +2 more
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Quantitation of hemoglobin in single erythrocytes with and without fetal hemoglobin

European Journal of Haematology, 1987
The hemoglobin content was determined by microspectrophotometry in single erythrocytes with and without fetal hemoglobin (Hb F) from 16 normal subjects, 30 patients with anemia of different etiology and severity and 20 individuals with thalassemic disorders. Hb F‐containing cells were identified by an indirect immunofluorescent method.
Meletis, J., Yataganas, X., Papavasiliou, E., Vaiopoulos, G., Fessas, Ph.   +4 more
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Hemoglobin C in association with hereditary persistence of fetal hemoglobin

Postgraduate Medicine, 1987
Hemoglobin C and hereditary persistence of fetal hemoglobin (HPFH) are an uncommon combination of hemoglobinopathies. Several tests are needed to verify this condition, among them hemoglobin electrophoresis and Kleihauer-Betke staining of a peripheral blood smear.
J. A. Lynch, Steven Lippmann, Alvin W. Martin, Manuel Martinez, Marie M. Keeling   +4 more
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Fetal Hemoglobin in Neonatal Anemia

Pediatrics, 1991
To the Editor.— A recent paper in Pediatrics by Bard and Prosmanne1 described an elevation of fetal hemoglobin (Hb-F) production in infants with bronchopulmonary dysplasia (BPD) and oxygen dependency. The authors described a novel approach to the evaluation of occult hypoxemia in infants, with potential application in a wide range of ...
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Transcriptional silencing of fetal hemoglobin by BCL11A

Annals of the New York Academy of Sciences, 2010
The β‐thalassemia syndromes are a major global health problem. Increased levels of fetal hemoglobin (HbF) ameliorate the clinical symptoms seen in this disease. By taking advantage of the natural variation in the level of HbF in various populations, we and others identified several common genetic variants in three major loci that regulate HbF levels ...
Vijay G. Sankaran, Jian Xu, Jian Xu, Jian Xu, Stuart H. Orkin, Stuart H. Orkin, Stuart H. Orkin   +6 more
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An Adult Homozygous for Persistent Fetal Hemoglobin

Annals of Internal Medicine, 1970
Abstract Target cells were predominant in the blood smear of a 53-year-old negro man admitted for a perforated duodenal ulcer.
Peter T. Rowley, William Siegel, Orland Penner, Robert Humber Cox, Walter Schroeder, Titus H.J. Huisman   +5 more
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Influences of Genetic Variation on Fetal Hemoglobin

Pediatric Hematology and Oncology, 2011
Fetal hemoglobin (HbF) plays a dominant role in ameliorating morbidity and mortality of hemoglobinopathies. The authors performed a replicated study following the genome-wide association study (GWAS) guidelines to identify the genetic mechanics that influence HbF. The authors recruited and phenotyped 312 unrelated β-thalassemia subjects.
Yunyan He, Weixiong Lin, Jianming Luo
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Pharmacologic Induction of Fetal Hemoglobin Production

Hematology/Oncology Clinics of North America, 2010
Reactivation of fetal hemoglobin (HbF) expression is an important therapeutic option in adult patients with hemoglobin disorders. The understanding of the developmental regulation of γ-globin gene expression was followed by the identification of a number of chemical compounds that can reactivate HbF synthesis in vitro and in vivo in patients with ...
George F. Atweh, Hassana Fathallah
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