Results 91 to 100 of about 850,904 (382)

Environmental contaminants exposure and preterm birth: a systematic review [PDF]

, 2019
Preterm birth is an obstetric condition associated with a high risk of infant mortality and morbidities in both the neonatal period and later in life, which has also a significant public health impact because it carries an important societal economic ...
Benedetti Panici, Pierluigi, MASCIULLO, LUISA, Piacenti, Ilaria, Porpora, Maria Grazia, Rech, Francesco, Scaramuzzino, Sara   +5 more
core   +1 more source

Pharmacological activation of peroxisome proliferator‐activated receptor γ (PPAR‐γ) protects against hypoxia‐associated fetal growth restriction

The FASEB Journal, 2019
The hypoxia of high‐altitude (HA) residence increases the risk of intrauterine growth restriction (IUGR) and preeclampsia 3‐fold, augmenting perinatal morbidity and mortality and the risk for childhood and adult disease. Currently, no effective therapies
Sydney L. Lane, R. Blair Dodson, Alexandrea S. Doyle, Haemin Park, H. Rathi, Christopher J. Matarrazo, L. Moore, R. Lorca, G. Wolfson, C. Julian   +9 more
semanticscholar   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Transcriptomics Modeling of the Late-Gestation Fetal Pituitary Response to Transient Hypoxia. [PDF]

PLoS ONE, 2016
BACKGROUND:The late-gestation fetal sheep responds to hypoxia with physiological, neuroendocrine, and cellular responses that aid in fetal survival. The response of the fetus to hypoxia represents a coordinated effort to maximize oxygen transfer from the
Charles E Wood, Eileen I Chang, Elaine M Richards, Maria Belen Rabaglino, Maureen Keller-Wood   +4 more
doaj   +1 more source

Labour ward incidents and potential claims - Lessons learned from research [PDF]

, 2008
This paper provides an insight into the underlying factors involved in potential cerebral palsy and/or shoulder dystocia claims. The research was undertaken to identify the root causes of 37 cases of birth asphyxia in term infants severe enough to ...
Ashcroft, B
core   +2 more sources

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Hypoxia Preconditioning Increases Survival and Decreases Expression of Toll-like Receptor 4 in Pulmonary Artery Endothelial Cells Exposed to Lipopolysaccharide [PDF]

, 2013
Pulmonary or systemic infections and hypoxemic respiratory failure are among the leading causes of admission to intensive care units, and these conditions frequently exist in sequence or in tandem.
Ali, Irshad, Audi, Said H., Densmore, John C., Husnain, Fouad, Jacobs, Elizabeth R., Konduri, G. Ganesh, Medhora, Meetha, Nanchal, Rahul   +7 more
core   +2 more sources

The role of cCTG in predicting Fetal hypoxia and Acidosis

Ultraschall in der Medizin - European Journal of Ultrasound, 2008
Objective: to evaluate the correlation between the short term variability during labour and the hypoxic fetal status. Methods: A prospective study was performed from Jan 2006 and Nov 2006 on 35 pregnant women near term or to at term in labour. 15 out of 35 had physiological fetal heart rate patterns.
Zambon A, Cosmi E, Savino RM, Gerace F, Monegato G, FAIS, PAOLO   +5 more
openaire   +4 more sources

Hypoxia and Oxidative Stress Are Associated with Reduced Fetal Growth in Twin and Undernourished Sheep Pregnancies

Animals, 2018
Simple Summary Twin gestations in sheep are economically more important than single ones; however, twins are born with lower weight, resulting in higher mortality and lower postnatal growth.
F. Sales, O. Peralta, Eileen Narbona, S. McCoard, M. De los Reyes, A. González-Bulnes, V. H. Parraguez   +6 more
semanticscholar   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source