Results 121 to 130 of about 850,904 (382)

Antitumoral Efficacy of AuNRs‐Laden ECFCs In Vitro and In Vivo: Decoding the Heat and Rays Combo Treatment in Breast Cancer and Melanoma Cells

Advanced Healthcare Materials, EarlyView.
Endothelial Colony Forming Cells (ECFCs) acted as cellular cyborgs, stealthily transporting gold nanorods (AuNRs) into tumors to enable targeted near‐infrared (NIR) hyperthermia combined with radiotherapy. This approach triggers ferroptosis in melanoma and inhibits autophagy in breast cancer, revealing a tumor‐specific response to nanomaterial‐assisted
Cecilia Anceschi, Francesca Scavone, Paolo Armanetti, Luca Menichetti, Claudia Catarinicchia, Claudia Borri, Fulvio Ratto, Filippo Micheletti, Noemi Formica, Jessica Ruzzolini, Elena Frediani, Anastasia Chillà, Francesca Margheri, Mirko Severi, Rita Traversi, Patrizia Nardini, Daniele Guasti, Mario Del Rosso, Tommaso Del Rosso, Lisa Giovanelli, Cinzia Talamonti, Monica Mangoni, Isacco Desideri, Silvia Burchielli, Fabiola Pajar, Gabriella Fibbi, Anna Laurenzana   +26 more
wiley   +1 more source

Release of ATP in the ventral medulla during hypoxia in rats: role in hypoxic ventilatory response [PDF]

, 2005
P2X2 receptor subunits of the ATP-gated ion channels are expressed by physiologically identified respiratory neurons in the ventral respiratory column, implicating ATP in the control of respiratory activity.
Dale, Nicholas, Gourine, Alexander V., Llaudet, Enrique, Spyer, K. Michael   +3 more
core   +2 more sources

Fetal Hypoxia

, 2014
Volume 5 • Issue 4 • 1000e121 J Health Med Inform ISSN: 2157-7420 JHMI, an open access journal Intrauterine fetus tends to be hypoxic, because a fetus is oxygenated via placental transfer, and umbilical arterial blood PO2 is usually below 50 mmHg which ...
K. Maeda
semanticscholar   +1 more source

Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development

Scientific Reports, 2017
Some neuropsychiatric disease, including schizophrenia, may originate during prenatal development, following periods of gestational hypoxia and placental oxidative stress.
T. Phillips, Hannah Scott, D. Menassa, Ashleigh L. Bignell, A. Sood, J. Morton, T. Akagi, Koki Azuma, Mark F. Rogers, Catherine E. Gilmore, G. Inman, Simon Grant, Yealin Chung, Mais M. Aljunaidy, C. Cooke, B. Steinkraus, A. Pocklington, A. Logan, G. Collett, Helena Kemp, P. Holmans, M. Murphy, T. Fulga, A. Coney, M. Akashi, S. Davidge, P. Case   +26 more
semanticscholar   +1 more source

Geometrically Controlled WNT Activation Drives Intestinal Morphogenesis

Advanced Healthcare Materials, EarlyView.
Crypt‐villi‐like morphogenesis can be driven and controlled via architectural patterns in colorectal cells with the use of digital light processing printing. The resulting mini tissues exhibit budding structures and functionality, as evidenced by increased mucin expression.
Nathaniel C. Burmas, Arlyn M. Fabian, Amoli Vanavadiya, Quinton Smith   +3 more
wiley   +1 more source

Use of Doppler indices in prediction of Acute Fetal Hypoxia – Proposed Staging System [PDF]

Al Ameen Journal of Medical Sciences, 2017
Background: Till now multiple studies regarding Doppler indices in Obstetrics have concentrated on detection of chronic hypoxia, publications have been silent on early detection of fetal hypoxia before the damage sets in.
P.T. Jadhav, Rajani Jadhav, Kartik Jadhav, Thilotama Naidu, J.V. Mundewadi, Nitin Tikare   +5 more
doaj  

Mesenchymal Stromal Cell‐Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia‐Ischemia

Stem Cells Translational Medicine, 2016
Preterm neonates are susceptible to perinatal hypoxic‐ischemic brain injury, for which no treatment is available. In a preclinical animal model of hypoxic‐ischemic brain injury in ovine fetuses, we have demonstrated the neuroprotective potential of ...
D. Ophelders, T. Wolfs, Reint K Jellema, A. Zwanenburg, P. Andriessen, T. Delhaas, Anna-Kristin Ludwig, S. Radtke, Vera Peters, Leon E W Janssen, B. Giebel, B. Kramer   +11 more
semanticscholar   +1 more source

Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases

Advanced Materials, EarlyView.
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu, Rockie Haiyao Ding, Zixuan Zhao, Clara Yieh Lin Chong, Ruochii You, Hengjia Zhou, Dong Hua Seah, Wei Qiang Leow, Hong Kit Lim, Sukanya Shyamasundar, Kanishka Fernando, Fathima Farzana Kuthubudeen, Gillian Ng, Chor Yong Tay, Narayanan Gopalakrishna Iyer, Chin‐Ann Johnny Ong, Eliza Li Shan Fong   +16 more
wiley   +1 more source

Fetal renal artery flow and renal echogenicity in the chronically hypoxic state. [PDF]

, 2000
peer reviewedThe object of this study was to investigate the fetal renal arterial blood flow in normal and hyperechogenic kidneys during the third trimester of gestation. The pregnancies screened were all chronically hypoxic. Depending on the etiology of
Suranyi, Andrea, Streitman, Karoly, Pal, Attila, Nyari, Tibor, Retz, Cristine, Foidart, Jean-Michel, Schaaps, Jean-Pierre, Kovacs, Lazlo   +7 more
core   +1 more source

Combined fetal inflammation and postnatal hypoxia causes myelin deficits and autism‐like behavior in a rat model of diffuse white matter injury

Glia, 2017
Diffuse white matter injury (WMI) is a serious problem in extremely preterm infants, and is associated with adverse neurodevelopmental outcome, including cognitive impairments and an increased risk of autism‐spectrum disorders.
Erik van Tilborg, E. Achterberg, C. M. van Kammen, A. van der Toorn, F. Groenendaal, R. Dijkhuizen, C. Heijnen, L. Vanderschuren, M. Benders, C. Nijboer   +9 more
semanticscholar   +1 more source