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Fetal cerebrovascular response to chronic hypoxia—implications for the prevention of brain damage [PDF]

Journal of Maternal-Fetal and Neonatal Medicine, 2006
Fetal hypoxia is one of the leading causes of perinatal morbidity and mortality. One of the most severe sequels of fetal hypoxic insult is the development of perinatal brain lesions resulting in a spectrum of neurological disabilities, from minor ...
Aida Salihagic-Kadic, Milan Koß, P Arbeille   +2 more
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Fetal metabolic responses to hypoxia

Reproduction, Fertility and Development, 1995
It has been known for may years that hypoxaemia in the fetus induces a number of biophysical, cardiovascular, endocrine and metabolic responses by the fetus, some of which are not sustained if the period of hypoxaemia is extended. For instance, fetal breathing and body movements and the circulating concentrations of many of the stress-related hormones ...
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Doppler velocimetry in the evaluation of fetal hypoxia

Journal of Perinatal Medicine, 2001
Knowledge of fetal hemodynamic physiology has developed enormously during the last two decades due to Doppler ultrasound. Some of this knowledge has been utilized for routine surveillance of high-risk pregnancies. The prediction of fetal hypoxia before the development of life lasting sequel is of major importance, especially in the very premature case ...
S, Gudmundsson, M, Dubiel
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Chronic hypoxia alters maternal uterine and fetal hemodynamics in the full-term pregnant guinea pig

American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 2017
Placental hypoxia is associated with maternal hypertension, placental insufficiency, and fetal growth restriction. In the pregnant guinea pig, prenatal hypoxia during early gestation inhibits cytotrophoblast invasion of spiral arteries, increases ...
Sifa Turan, Graham W Aberdeen, Loren P Thompson   +2 more
exaly   +2 more sources

Moderate Hypoxia Exposure and Fetal Development

Archives of Environmental Health: An International Journal, 1975
Exposure of rabbits to 15.5% oxygen during pregnancy resulted in a 17% decrease of birth weight and a neonatal mortality of 19% as opposed to 1% in the control groups, just corresponding to the effects obtained previously by moderate exposure of pregnant rabbits to carbon monoxide. Since additive effects of hypoxia exposure and carbon monoxide exposure
P, Astrup, D, Trolle, H M, Olsen, K, Kjeldsen   +3 more
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Iatrogenic Fetal Hypoxia

1971
Iatrogenic diseases are defined as diseases due to medical interference. They must be as old as medicine itself. Their particular and almost tragic pecularity is given by the fact that measures taken to improve the health of human beings finally exert an opposite effect and are the cause of a new disease.
F. Kubli, H. Rüttgers
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Intrapartum Cardiotocography and Fetal Pulse Oximetry in Assessing Fetal Hypoxia

Obstetrical & Gynecological Survey, 2002
AbstractObjectives: A retrospective analysis of short‐term variability (STV), a cardiotocography (CTG) parameter, in relation to fetal blood saturation values (FSpO2) obtained by fetal pulse oximetry. Methods: The study included 26 healthy pregnant women monitored continuously during delivery with both cardiotocography and fetal pulse oximetry. Results:
B, Leszczynska-Gorzelak, E, Poniedzialek-Czajkowska, J, Oleszczuk   +2 more
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Is fetal insulin secretion affected by fetal hypoxia?

Early Human Development, 1990
Fifty-five pregnant Rhesus isoimmunized women were subjected to fetal blood sampling or fetal blood transfusion on 135 occasions. Glucose and C-peptide concentrations were measured in fetal blood, in addition to the routine investigations for complete blood count, blood gases and lactate concentration, in order to investigate whether fetal insulin ...
M, Stangenberg, P, Sasidharan
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Relationship Between Fetal Hypoxia and Endothelin-1 in Fetal Circulation

Journal of Cardiovascular Pharmacology, 1991
The role of endothelin-1 (ET-1), a potent vasoconstrictor peptide secreted by endothelial cells, in fetal circulation was investigated in relation to fetal hypoxia. Umbilical venous blood was obtained from 23 subjects who delivered between 36 and 41 weeks of gestation.
K, Hashiguchi, K, Takagi, M, Nakabayashi, Y, Takeda, S, Sakamoto, M, Naruse, K, Naruse, H, Demura   +7 more
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Fetal arterial Doppler-IUGR and hypoxia

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1997
Vascular resistances of various fetal areas are assessed by Doppler ultrasound. The PI, RI and S/D indices are measured on the cerebral, renal, aortic and umbilical Doppler spectrum. Ratios of these indices based on the comparison of the cerebral (Rc) and the umbilical (Rp) resistances, or carotid (Rcc) and umbilical resistances, or cerebral (Rc) and ...
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