Placental Evidence of Intrauterine Stress: Mechanisms, Timing, and Links to Perinatal Brain Injury. [PDF]
Kim CF, Carreon CK.
europepmc +1 more source
Maternal and neonatal outcomes in Gaza amid armed hostilities in 2025
Abstract Objective This study documents facility‐based maternal, obstetric, and neonatal outcomes and associated conflict‐related exposures and living conditions among pregnancy‐related encounters at Al‐Helou Maternity Hospital in Gaza from late April to early September 2025, with a small number of additional encounters recorded at Al‐Shifa Medical ...
Shaymaa Abuhaiba +16 more
wiley +1 more source
Morphological Features and HIF1-Dependent Processes in the Brain of Progeny of Female Rats Exposed to Maternal Hypoxia. [PDF]
Potapova S +4 more
europepmc +1 more source
Abstract Objective Recurrent fetal heart rate (FHR) decelerations without acidosis are frequently observed during labor; however, the underlying autonomic mechanisms remain incompletely understood. This study explored fetal autonomic responses to recurrent decelerations using FHR and FHR variability (FHRV) parameters.
Shoichi Magawa +9 more
wiley +1 more source
Intrapartum CTG characteristics associated with isolated single umbilical artery in term fetuses: A matched case-control study. [PDF]
Berben PBQ +5 more
europepmc +1 more source
MicroRNA‐210 level as a biomarker for pre‐eclampsia severity: A systematic review and meta‐analysis
Abstract Background Pre‐eclampsia is a serious pregnancy‐related syndrome lacking accurate prognostic markers. MicroRNA‐210, overexpressed in the circulation of women with pre‐eclampsia, has recently emerged as a promising biomarker. Objectives We conducted a systematic review and meta‐analysis to evaluate the relationship between miR‐210 levels and ...
Dávid Márai +8 more
wiley +1 more source
Decidual macrophage‐mediated ferroptosis in trophoblasts leads to recurrent spontaneous abortion
Decidual macrophages from recurrent spontaneous abortion (RSA) patients promote trophoblast ferroptosis and impair trophoblast cell function. Mechanistically, the CXCL2/NF‐κB/HMOX1 axis mediates this effect. Conversely, trophoblasts co‐cultured with RSA decidual macrophages induce pro‐inflammatory macrophage polarization through IL‐6/JAK2/STAT3 ...
Xin Chen +9 more
wiley +1 more source
USP22 suppresses trophoblast cell necroptosis in preeclampsia by stabilizing KAT2A-mediated histone acetylation at the SFRP1 promoter. [PDF]
He L, Zhan F, Zheng S, Lin N.
europepmc +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Understanding Preeclampsia: Integrating Placental Dysfunction, Immune Dysregulation and microRNA-Mediated Epigenetic Regulation. [PDF]
Procopciuc LM +3 more
europepmc +1 more source

