Results 251 to 260 of about 850,904 (382)

A pH‐Sensitive Nanosized Covalent–Organic Polymer for Enhanced Tumor Photodynamic Immunotherapy by Hypoxia Relief and STAT3 Inhibition

Advanced Science, EarlyView.
The nanosized covalent organic polymer composed of photosensitizer porphyrin, pyruvate kinase inhibitor vitamin K3, and STAT3 inhibitor WP1066 is prepared for enhanced photodynamic immunotherapy by simultaneous hypoxia relief and STAT3 inhibition. Abstract Photodynamic therapy (PDT) is a promising cancer therapy modality by generating reactive oxygen ...
Lei Lei, Wenbin Dai, Jinchao Zhao, Angfeng Jiang, Haisheng Peng, Qiao Jin, Xiaojing Li, Zhe Tang   +7 more
wiley   +1 more source

Adverse Intrauterine Conditions Diminish the Fetal Defense Against Acute Hypoxia by Increasing Nitric Oxide Activity

, 2002
David S. Gardner, Abigail L. Fowden, Dino A. Giussani   +2 more
openalex   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

A new animal model for uterine torsion and uterine ischemia-reperfusion studies, but not fetal hypoxia studies. [PDF]

Animal Model Exp Med, 2018
Dogan H, Timurkaan N, Saat N, Seker I, Risvanli A.   +4 more
europepmc   +1 more source

VEGF expression and microvascular responses to severe transient hypoxia in the fetal sheep brain [PDF]

, 2012
Ana A. Baburamani, Margie Castillo-Meléndez, David W. Walker   +2 more
openalex   +1 more source

Chronic intrauterine hypoxia alters neurodevelopment in fetal sheep

Journal of Thoracic and Cardiovascular Surgery, 2019
Kendall M. Lawrence, P. McGovern, A. Mejaddam, A. Rossidis, Heron D. Baumgarten, Aimee G. Kim, J. Grinspan, D. Licht, R. Didier, A. Vossough, E. Radaelli, J. Rychik, L. Song, W. Peranteau, M. Davey, A. Flake, W. Gaynor   +16 more
semanticscholar   +1 more source

Lysosome‐Featured Cell Aggregate‐Released Extracellular Vesicles Regulate Iron Homeostasis and Alleviate Post‐Irradiation Endothelial Ferroptosis for Mandibular Regeneration

Advanced Science, EarlyView.
Lysosomal redistribution occurs via extracellular vesicles in multi‐stem cell aggregates and controls iron homeostasis for safeguarding cell aggregation. These cell aggregate‐released extracellular vesicles (CA‐EVs) rescue lysosomal impairments and exert anti‐ferroptosis effects in recipient irradiated endothelial cells.
Yuan‐Yuan Li, Bo Ma, Jia‐Wei Lu, Kai‐Chao Zhang, Chao Ma, Sheng‐Feng Bai, Yan‐Jiao Li, Si‐Qi Ying, Wei‐Zong Weng, Kai Zhang, Xi‐Wang Hu, Rang Li, Chen‐Xi Zheng, Xiao‐Ru Xu, Ji Chen, Fang Jin, Hao‐Kun Xu, Jian‐Wei Xie, Yan Jin, Yi Shuai, Bing‐Dong Sui   +20 more
wiley   +1 more source

Nanofabricated Bacterial Cell Walls with Intrinsic Peroxidase‐Mimicking and Sonodynamic Activities for Cancer Combination Treatment

Advanced Science, EarlyView.
Bacterial cell walls (CWs) extracted from Porphyromonas gingivalis are nanofabricated to form the CW vesicles (CWV), which have intrinsic peroxidase‐mimicking and sonodynamic activities due to the presence of µ‐oxo bisheme and meanwhile retain a large amount of lipopolysaccharide.
Meng Yang, Yang Meng, Junling Li, Liya Bai, Yuanyuan Cheng, Yuanyuan Liu, Mingxin Cao, Xiaoying Yang, Yinsong Wang, Yang Liu   +9 more
wiley   +1 more source

Effect of normoxia and hypoxia on K+ current and resting membrane potential of fetal rabbit pulmonary artery smooth muscle

, 2005
Zhigang Hong, Ε. Kenneth Weir, Anthony Varghese, Andrea Olschewski   +3 more
openalex   +1 more source

Maternal hypoxia and caffeine exposure depress fetal cardiovascular function during primary organogenesis [PDF]

, 2012
Nobuo Momoi, Joseph P. Tinney, Bradley B. Keller, Kimimasa Tobita   +3 more
openalex   +1 more source