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Insufficient oxygen supply (hypoxia) during fetal development leads to cardiac remodeling and a predisposition to cardiovascular disease in later life. Previous work has shown hypoxia causes oxidative stress in the fetal heart and alters the activity and
Kerri L M Smith+12 more
semanticscholar +1 more source
Types of intrapartum hypoxia in the newborn at term with metabolic acidemia: A retrospective study
Introduction In the most recent recommendations of the International Federation of Gynecology and Obstetrics (FIGO), a chapter was dedicated to the physiological approach and to the description of fetal mechanisms developed to respond to hypoxia.
Léa Descourvieres+7 more
doaj +1 more source
Hypoxia and Fetal Heart Development [PDF]
Fetal hearts show a remarkable ability to develop under hypoxic conditions. The metabolic flexibility of fetal hearts allows sustained development under low oxygen conditions. In fact, hypoxia is critical for proper myocardial formation. Particularly, hypoxia inducible factor 1 (HIF-1) and vascular endothelial growth factor play central roles in ...
Andrew J. Patterson, Lubo Zhang
openaire +3 more sources
Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism, intervention, and long-term consequences [PDF]
Background: Intrauterine growth restriction is associated with an increased future risk for developing cardiovascular diseases. Hypoxia in utero is a common clinical cause of fetal growth restriction.
AM Katz+62 more
core +15 more sources
Analysis of development of fetal hypoxia as a common complication of pregnancy and labor
Due to insufficient oxygen supply to the fetus, which is called hypoxia, adverse changes occur in its body. In the total number of births, it is 10,5%. Fetal hypoxia is not an independent disease.
E. V. Semeleva+2 more
doaj +1 more source
Is obesity in pregnancy associated with signs of chronic fetal hypoxia?
The prevalence of obesity in pregnancy is increasing worldwide. Maternal obesity increases risks of severe fetal and neonatal complications. The underlying pathophysiological mechanisms are unclear. One possible contributing factor could be chronic fetal
Hanna Åmark+4 more
semanticscholar +1 more source
Individuals with intrauterine growth restriction (IUGR) are at an increased risk for neurodevelopmental impairment. Fetal cortical neurogenesis is a time-sensitive process in which fetal neural stem cells (NSCs) follow a distinct pattern of layer ...
Fu-Sheng Chou+4 more
doaj +1 more source
Modernization of obstetric care for fetal hypoxia is proposed by hyperventilating the mother’s lungs with oxygen before the first symptoms of oxygen poisoning, General hypothermia of her body, and local hypothermia of the fetal head in the final period ...
A. Urakov, N. Urakova
semanticscholar +1 more source
Fetal hypoxia and programming of matrix metalloproteinases [PDF]
Fetal hypoxia adversely affects the brain and heart development, yet the mechanisms responsible remain elusive. Recent studies indicate an important role of the extracellular matrix in fetal development and tissue remodeling. The matrix metalloproteinases (MMPs) and their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs) have been ...
Wenni Tong, Lubo Zhang
openaire +3 more sources
European Community Multi-Center Trial "Fetal ECG Analysis During Labor": ST plus CTG analysis [PDF]
This report form part of the European Community Multi-Center Trial "Fetal ECG Analysis during Labor". Aim of this prospective trial was to identify changes in the fetal ECG waveform with cases of verified fetal hypoxia.
Erkkola, Rhisto+5 more
core +1 more source