Results 31 to 40 of about 110,385 (298)
A maternal high-fat diet induces fetal origins of NASH-HCC in mice
Scientific Reports, 2022 Maternal overnutrition affects offspring susceptibility to nonalcoholic steatohepatitis (NASH). Male offspring from high-fat diet (HFD)-fed dams developed a severe form of NASH, leading to highly vascular tumor formation.
Takao Takiyama +14 more
doaj +1 more source
Causes and mechanisms of intrauterine hypoxia and its impact on the fetal cardiovascular system: a review [PDF]
, 2010 Until today the role of oxygen in the development of the fetus remains controversially discussed. It is still believed that lack of oxygen in utero might be responsible for some of the known congenital cardiovascular malformations.
Hutter, Damian +5 more
core +1 more source
Mouse models for preeclampsia: disruption of redox-regulated signaling [PDF]
, 2009 The concept that oxidative stress contributes to the development of human preeclampsia has never been tested in genetically-defined animal models. Homozygous deletion of catechol-Omethyl transferase (Comt-/-) in pregnant mice leads to human preeclampsia ...
Chambers, Anne E. +8 more
core +1 more source
ST analysis of fetal electrocardiography in labor
, 2011 Since its introduction more than 40 years ago, electronic fetal monitoring has become widely used for intrapartum surveillance to determine fetal wellbeing in labor.
I. Amer-Wåhlin +5 more
core +2 more sources
RhoA activation by hypoxia in pulmonary arterial smooth muscle cells is age and site specific
, 2004 Hypoxia induces vasoconstriction of pulmonary arteries through contraction of smooth muscle cells (SMCs). The GTPase RhoA regulates smooth muscle contractility and actin cytoskeletal remodeling through the Rho-associated kinase ( ROCK).
Bailly, K +6 more
core +1 more source
Hypoxia and Mitochondrial Dysfunction in Pregnancy Complications
Antioxidants, 2021 Hypoxia is a common and severe stress to an organism’s homeostatic mechanisms, and hypoxia during gestation is associated with significantly increased incidence of maternal complications of preeclampsia, adversely impacting on the fetal development and ...
Xiang-Qun Hu, Lubo Zhang
doaj +1 more source
Animal models of fetal growth restriction: Considerations for translational medicine.
, 2015 Fetal growth restriction (FGR) is the failure of a fetus to reach its full genetic growth potential. It occurs in up to 8% of pregnancies, and after premature birth is the second leading cause of infant mortality and morbidity.
David, AL +3 more
core +1 more source
Fetal blood vessel count increases in compensation of hypoxia in premature placentas [PDF]
Universa Medicina, 2015 Background Prematurity refers to live births before 37 weeks of gestation, wherein the baby is born before the body and its organ systems achieve perfect maturity, and this disorder is still a global problem.
K. Kartini +4 more
doaj +1 more source
The role of cyclic nucleotide on fetal and neonantal erythropoiesis
, 1974 For the purpose to reveal the changes in stimulatory effect of dibutyryl-cyclic- AMP on erythropoiesis during ontogenetic development, the author studied syntheses of DNA, RNA and protein of erythroid cells in fetal liver, neonatal and adult bone marrows
Tada, Hiroshi
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source