Results 11 to 20 of about 106,528 (261)
Hypoxia and Fetal Heart Development [PDF]
Current Molecular Medicine, 2010 Fetal hearts show a remarkable ability to develop under hypoxic conditions. The metabolic flexibility of fetal hearts allows sustained development under low oxygen conditions. In fact, hypoxia is critical for proper myocardial formation. Particularly, hypoxia inducible factor 1 (HIF-1) and vascular endothelial growth factor play central roles in ...
A J, Patterson, L, Zhang
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Circulating MicroRNAs in maternal blood as potential biomarkers for fetal hypoxia in-utero. [PDF]
PLoS ONE, 2013 Stillbirth affects 1 in 200 pregnancies and commonly arises due to a lack of oxygen supply to the fetus. Current tests to detect fetal hypoxia in-utero lack the sensitivity to identify many babies at risk.
Clare L Whitehead +5 more
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Frontiers in Cell and Developmental Biology, 2022 Individuals with intrauterine growth restriction (IUGR) are at an increased risk for neurodevelopmental impairment. Fetal cortical neurogenesis is a time-sensitive process in which fetal neural stem cells (NSCs) follow a distinct pattern of layer ...
Fu-Sheng Chou +4 more
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Effects of Prenatal Hypoxia on Nervous System Development and Related Diseases
Frontiers in Neuroscience, 2021 The fetal origins of adult disease (FOAD) hypothesis, which was proposed by David Barker in the United Kingdom in the late 1980s, posited that adult chronic diseases originated from various adverse stimuli in early fetal development.
Bin Wang +3 more
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Fetal hypoxia and programming of matrix metalloproteinases [PDF]
Drug Discovery Today, 2012 Fetal hypoxia adversely affects the brain and heart development, yet the mechanisms responsible remain elusive. Recent studies indicate an important role of the extracellular matrix in fetal development and tissue remodeling. The matrix metalloproteinases (MMPs) and their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs) have been ...
Wenni, Tong, Lubo, Zhang
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Chronic Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys
Frontiers in Physiology, 2017 Hypoxic environments at high altitude have significant effects on kidney injury. Following injury, renal primary cilia display length alterations. Primary cilia are mechanosensory organelles that regulate tubular architecture.
Kiumars Shamloo +9 more
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Bio-Protocol, 2022 Late-gestation transient intrauterine hypoxia is a common cause of birth injury. It can lead to long-term neurodevelopmental disabilities even in the absence of gross anatomic injury. Currently, postnatal models of hypoxia–ischemia are most commonly used
Elyse Gadra, Ana Cristancho
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مجله دانشگاه علوم پزشکی گرگان, 2022 Background and Objective: Hypoxia is one of the most common clinical stresses that occur during pregnancy, which has adverse effects on fetal development. Fish oil, with its antioxidant properties, prevents fetal disorders during pregnancy.
Kaveh Khazaeel +3 more
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Antenatal Hypoxia Accelerates the Onset of Alzheimer’s Disease Pathology in 5xFAD Mouse Model
Frontiers in Aging Neuroscience, 2020 Alzheimer’s disease (AD) is a chronic neurodegenerative disorder associated with cognitive impairment and later dementia among the elderly. Mounting evidence shows that adverse maternal environments during the fetal development increase the risk of ...
Guofang Shen +4 more
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Biomedical Papers, 2019 Objective: To explore whether miR-210 expression can be used as a diagnostic and prognostic marker in acute fetal hypoxia. Methods: Whole blood samples of 29 women and their fetuses without hypoxia and 24 women and their fetuses with hypoxia were ...
Barbara Vonkova +4 more
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