Results 21 to 30 of about 110,385 (298)
Hypoxia-induced signaling in angiogenesis : role of mTOR, HIF and Angiotensin II [PDF]
This thesis includes the work of four different projects I have been following during my time as a PhD student; (1) the characterization of mTOR-associated signaling and endothelial cell proliferation in response to hypoxia, and (2) identification of ...
Petrimpol, Marco Renato
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Fetal hypoxia and programming of matrix metalloproteinases [PDF]
Fetal hypoxia adversely affects the brain and heart development, yet the mechanisms responsible remain elusive. Recent studies indicate an important role of the extracellular matrix in fetal development and tissue remodeling. The matrix metalloproteinases (MMPs) and their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs) have been ...
Wenni, Tong, Lubo, Zhang
openaire +2 more sources
Release of ATP in the ventral medulla during hypoxia in rats: role in hypoxic ventilatory response [PDF]
P2X2 receptor subunits of the ATP-gated ion channels are expressed by physiologically identified respiratory neurons in the ventral respiratory column, implicating ATP in the control of respiratory activity.
Spyer, K. Michael +7 more
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Chronic Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys
Hypoxic environments at high altitude have significant effects on kidney injury. Following injury, renal primary cilia display length alterations. Primary cilia are mechanosensory organelles that regulate tubular architecture.
Kiumars Shamloo +9 more
doaj +1 more source
Late-gestation transient intrauterine hypoxia is a common cause of birth injury. It can lead to long-term neurodevelopmental disabilities even in the absence of gross anatomic injury. Currently, postnatal models of hypoxia–ischemia are most commonly used
Elyse Gadra, Ana Cristancho
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Background and Objective: Hypoxia is one of the most common clinical stresses that occur during pregnancy, which has adverse effects on fetal development. Fish oil, with its antioxidant properties, prevents fetal disorders during pregnancy.
Kaveh Khazaeel +3 more
doaj
Antenatal Hypoxia Accelerates the Onset of Alzheimer’s Disease Pathology in 5xFAD Mouse Model
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder associated with cognitive impairment and later dementia among the elderly. Mounting evidence shows that adverse maternal environments during the fetal development increase the risk of ...
Guofang Shen +4 more
doaj +1 more source
Objective: To explore whether miR-210 expression can be used as a diagnostic and prognostic marker in acute fetal hypoxia. Methods: Whole blood samples of 29 women and their fetuses without hypoxia and 24 women and their fetuses with hypoxia were ...
Barbara Vonkova +4 more
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Fetal chronic hypoxia leads to intrauterine growth restriction (IUGR), which is likely to reduce oxygen delivery to the brain and induce long-term neurological impairments.
Emilio A. Herrera +1 more
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Prenatal Hypoxia and Placental Oxidative Stress: Insights from Animal Models to Clinical Evidences
Hypoxia is a common form of intrauterine stress characterized by exposure to low oxygen concentrations. Gestational hypoxia is associated with the generation of reactive oxygen species.
Serena Silvestro +4 more
doaj +1 more source

