Results 61 to 70 of about 106,528 (261)

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

Advanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan, Yanhong Chen, Jingjing Hu, Chunting Wang, Huanhuan Liu, Defan Yao, Dengbin Wang   +6 more
wiley   +1 more source

Diagnostic value of combined maternal cardiac work and fetoplacental circulation parameters in detecting fetal intrauterine hypoxia in preeclamptic women

Scientific Reports
To investigate the correlation between fetoplacental circulation and maternal left ventricular myocardial work (MW) parameters in patients with preeclampsia (PE) and the prediction of fetal hypoxia.
Jinghao Du, Jing Zhao, Wanyan LI, Lihong Wang   +3 more
doaj   +1 more source

Intrauterine exposure to chronic hypoxia in the rat leads to progressive diastolic function and increased aortic stiffness from early postnatal developmental stages

Physiological Reports, 2020
Aim We sought to explore whether fetal hypoxia exposure, an insult of placental insufficiency, is associated with left ventricular dysfunction and increased aortic stiffness at early postnatal ages.
Praveen Kumar, Jude S. Morton, Amin Shah, Victor Do, Consolato Sergi, Jesus Serrano‐Lomelin, Sandra T. Davidge, Donna Beker, Jody Levasseur, Lisa K. Hornberger   +9 more
doaj   +1 more source

Dynamic Mechanical Loading Modulates Extracellular Vesicle Production and Cargo in Meniscus Fibrochondrocytes

Advanced Materials Interfaces, EarlyView.
Dynamic mechanical loading of outer meniscus fibrochondrocytes increases extracellular vesicle (EV) yield and alters EV composition. When applied to progenitor cells, these mechanically primed EVs modulate the expression of matrix‐related genes.
Catherine Cheung, Zizhao Li, Sung‐Han Jo, Se‐Hwan Lee, Il Keun Kwon, Jina Ko, Su Chin Heo   +6 more
wiley   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

HARDWARE AND SOFTWARE COMPLEX FOR FUNCTIONAL STATE MONITORING OF MOTHER AND FETUS

Бюллетень сибирской медицины, 2014
Text abstract Mother’s and fetus’s health are very important in present time. With timely diagnosis perinatal pathology, birth injuries, antenatal stillbirths and newborn perinatal death can be prevented. At the moment in the world there are no complexes
I. V. Tolmachyov, K. S. Brazovsky, A. S. Tsverova, V. S. Ripenko   +3 more
doaj   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Amniotic fluid embolism as an immunocoagulatory catastrophic anaphylactoid syndrome

Акушерство, гинекология и репродукция
Amniotic fluid embolism (AFE) is a rare, life-threatening obstetric complication, known in modern terminology as anaphylactoid syndrome of pregnancy (ASP).
A. R. Oskolkova, A. R. Khisamieva, V. O. Bitsadze, J. Kh. Khizroeva, N. A. Makatsariya, M. V. Tretyakova, N. R. Gashimova, K. N. Grigoreva, O. Yu. Panfilova, J.-Ch. Gris, I. Elalamy, G. Gerotziafas, E. D. Makatsariya   +12 more
doaj   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Alterações anatomopatológicas da placenta e variações do índice de Apgar Anatomic and pathological placenta alterations and Apgar score variations

Revista Brasileira de Saúde Materno Infantil, 2006
OBJETIVOS: descrever possíveis alterações anatomopatológicas placentárias associadas à hipóxia fetal, avaliada pelo índice de Apgar. MÉTODOS: foram estudadas 167 placentas de partos realizados no Hospital Escola da Universidade Federal do Triângulo ...
Rosana Rosa Miranda Corrêa, Ana Karina Marques Salge, Gustavo Augusto Ribeiro, Mara Lúcia Fonseca Ferraz, Marlene Antônia dos Reis, Eumenia Costa da Cunha Castro, Vicente de Paula Antunes Teixeira   +6 more
doaj   +1 more source