Results 81 to 90 of about 795,751 (338)

Theophylline Stimulates Fetal Breathing Movements during Hypoxia [PDF]

Pediatric Research, 1990
The respiratory responses to theophylline during normoxia and hypoxia were determined in 13 unanesthetized fetal sheep. Theophylline (plasma levels approximately 111 mumol/L) increased the incidence of fetal breathing movements measured over 120 min from 37.7 +/- 4.8% to 61.1 +/- 5.7% (SEM) in normoxic fetuses. In isocapnic hypoxia (arterial O2 tension
J M, Bissonnette, A R, Hohimer, C R, Chao, S J, Knopp, N F, Notoroberto   +4 more
openaire   +2 more sources

Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate

Advanced Healthcare Materials, EarlyView.
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang, Peiyuan Wang, Hildert Bronkhorst, Yurii Husiev, Ludovic Bretin, Maarten N. van Ginkel, Wen Sun, Sylvestre Bonnet   +7 more
wiley   +1 more source

Alterações anatomopatológicas da placenta e variações do índice de Apgar Anatomic and pathological placenta alterations and Apgar score variations

Revista Brasileira de Saúde Materno Infantil, 2006
OBJETIVOS: descrever possíveis alterações anatomopatológicas placentárias associadas à hipóxia fetal, avaliada pelo índice de Apgar. MÉTODOS: foram estudadas 167 placentas de partos realizados no Hospital Escola da Universidade Federal do Triângulo ...
Rosana Rosa Miranda Corrêa, Ana Karina Marques Salge, Gustavo Augusto Ribeiro, Mara Lúcia Fonseca Ferraz, Marlene Antônia dos Reis, Eumenia Costa da Cunha Castro, Vicente de Paula Antunes Teixeira   +6 more
doaj   +1 more source

Hypoxia and Oxidative Stress Are Associated with Reduced Fetal Growth in Twin and Undernourished Sheep Pregnancies

Animals, 2018
Simple Summary Twin gestations in sheep are economically more important than single ones; however, twins are born with lower weight, resulting in higher mortality and lower postnatal growth.
F. Sales, O. Peralta, Eileen Narbona, S. McCoard, M. De los Reyes, A. González-Bulnes, V. H. Parraguez   +6 more
semanticscholar   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Hypoxia in extravillous trophoblasts links maternal obesity and offspring neurobehavior

iScience
Summary: While maternal obesity (MO) is associated with neurobehavioral impairment (NBI) in offspring, the underlying mechanisms remain unknown. The placenta is thought to play a role in fetal programming.
Fatima Gunter-Rahman, Shayna Mallett, Frédérique White, Pierre-Étienne Jacques, Ravikiran M. Raju, Marie-France Hivert, Eunjung Alice Lee   +6 more
doaj   +1 more source

The Beneficial Effects of Melatonin Administration Following Hypoxia-Ischemia in Preterm Fetal Sheep

Frontiers in Cellular Neuroscience, 2017
Melatonin (MLT) is an endogenous hormone that controls circadian cycle. MLT has additional important properties that make it appealing as a neuroprotective agent—it is a potent anti-oxidant, with anti-apoptotic and anti-inflammatory properties.
T. Yawno, M. Mahen, Jingang Li, M. Fahey, G. Jenkin, Suzanne L. Miller   +5 more
semanticscholar   +1 more source

Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds

Advanced Healthcare Materials, EarlyView.
3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar, Diego Caicedo‐Valdés, Susana B. Bravo, Isabel Rodriguez‐Moldes, Salvador D. Aznar‐Cervantes, Angel Concheiro, Carmen Alvarez‐Lorenzo, Luis Diaz‐Gomez   +7 more
wiley   +1 more source

HARDWARE AND SOFTWARE COMPLEX FOR FUNCTIONAL STATE MONITORING OF MOTHER AND FETUS

Бюллетень сибирской медицины, 2014
Text abstract Mother’s and fetus’s health are very important in present time. With timely diagnosis perinatal pathology, birth injuries, antenatal stillbirths and newborn perinatal death can be prevented. At the moment in the world there are no complexes
I. V. Tolmachyov, K. S. Brazovsky, A. S. Tsverova, V. S. Ripenko   +3 more
doaj   +1 more source

Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development

Scientific Reports, 2017
Some neuropsychiatric disease, including schizophrenia, may originate during prenatal development, following periods of gestational hypoxia and placental oxidative stress.
T. Phillips, Hannah Scott, D. Menassa, Ashleigh L. Bignell, A. Sood, J. Morton, T. Akagi, Koki Azuma, Mark F. Rogers, Catherine E. Gilmore, G. Inman, Simon Grant, Yealin Chung, Mais M. Aljunaidy, C. Cooke, B. Steinkraus, A. Pocklington, A. Logan, G. Collett, Helena Kemp, P. Holmans, M. Murphy, T. Fulga, A. Coney, M. Akashi, S. Davidge, P. Case   +26 more
semanticscholar   +1 more source