Results 191 to 200 of about 213,856 (269)

RTA‐408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Glioblastoma (GBM) is an aggressive brain tumor with poor prognosis owing to its high invasiveness and resistance to therapy. RTA‐408, a synthetic triterpenoid and nuclear factor erythroid 2‐related factor 2 activator, exhibits anti‐inflammatory and anti‐cancer properties; however, its effects on GBM remain unclear. This study investigated the
Hung‐Pei Tsai   +6 more
wiley   +1 more source

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

LncRNA NORAD Enhances Inflammatory Injury in Sepsis‐Associated Acute Lung Damage Through miR‐150‐5p/STAT1‐Dependent NF‐κB Activation

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu   +4 more
wiley   +1 more source

SARS-CoV-2 Chronic Intervillositis: Variations of Maternal Antiviral Response. [PDF]

open access: yesAm J Reprod Immunol
Kozlova D   +8 more
europepmc   +1 more source

Alterations in MicroRNA and Cytokine Expressions in Placental and Amniotic Tissues of COVID‐19 Affected Pregnant Women

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Since 2019, coronavirus disease 2019 (COVID‐19) has been associated with increased risks of preterm birth and placental complications. We prospectively investigated alterations in microRNAs (miRNAs) and cytokines in placental and amniotic tissues from pregnant women with and without COVID‐19 to evaluate the infection's impact on pregnancy ...
Wei‐Chun Chen   +3 more
wiley   +1 more source

Interstitial pneumonia and lymphocytic bronchiolitis with interstitial emphysema of unknown cause in Western Canadian fetal and neonatal beef calves. [PDF]

open access: yesJ Vet Diagn Invest
Goldsmith D   +8 more
europepmc   +1 more source

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song   +7 more
wiley   +1 more source

COVID-19 and Pregnancy: Key Findings. [PDF]

open access: yesScand J Immunol
Lima GG   +5 more
europepmc   +1 more source

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