Results 61 to 70 of about 213,856 (269)

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Systemic inflammatory responses to repeated and increasing endotoxin challenges in fetal sheep

Physiological Reports
Repeated low‐dose administration of lipopolysaccharide (LPS) attenuates subsequent fetal responses, which makes it challenging to investigate interventions to prolonged exposure.
Sanya Kathuria, Akash Gupta, Ayna R. Tracy, Rosa I. Luna Ramirez, Senthil Kumar Thulasingam, Nahla Zaghloul, Mohamed Ahmed, Sean W. Limesand   +7 more
doaj   +1 more source

Differences in Whole Blood Gene Expression Associated with Infection Time-Course and Extent of Fetal Mortality in a Reproductive Model of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection. [PDF]

PLoS ONE, 2016
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection of pregnant females causes fetal death and increased piglet mortality, but there is substantial variation in the extent of reproductive pathology between individual dams.
Jamie M Wilkinson, Andrea Ladinig, Hua Bao, Arun Kommadath, Paul Stothard, Joan K Lunney, John C S Harding, Graham S Plastow   +7 more
doaj   +1 more source

Inflammatory Response as a Mechanism of Perinatal Programming: Long-term Impact on Pulmonary and Renal Function? [PDF]

, 2012
RATIONALE: Temporal changes in the fetal environment, such as malnutrition and placental insufficiency induce intrauterine growth restriction (IUGR) and lead to a permanent changes of physiological processes later in life.
Alejandre Alcázar, Miguel Angel
core  

A lesson for cancer research : placental microarray gene analysis in preeclampsia [PDF]

, 2012
Tumor progression and pregnancy share many common features, such as immune tolerance and invasion. The invasion of trophoblasts in the placenta into the uterine wall is essential for fetal development, and is thus precisely regulated.
Louwen, Frank, Muschol-Steinmetz, Cornelia, Reinhard, Joscha, Reitter, Anke, Yuan, Juping   +4 more
core   +2 more sources

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Pilot Study Analyzing Combination of Point-of-Care Echocardiography and Clinical Correlation in Unveiling Cryptic Multi-Inflammatory Syndrome in Neonates during Coronavirus Disease 2019 Pandemic

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2022
Introduction: Coronavirus disease 2019 (COVID-19), an extremely contagious pandemic, caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), originated from Wuhan, Hubei province, in China in December 2019.
Maitri Chaudhuri, Munesh Tomar, Seema Gaonkar, Anuj Rastogi, Arvind Shenoi   +4 more
doaj   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

Significance of C-reactive protein in predicting fetal inflammatory response syndrome

Polish Gynaecology, 2015
The aim of the study was to identify and evaluate a possible correlation between C-reactive protein (CRP) concentration in maternal blood and the risk of developing fetal inflammatory syndrome (FIRS).The study included 158 infants born at 22-34 weeks of gestation and their mothers.
Daiva, Bartkeviciene, Ingrida, Pilypiene, Diana, Ramasauskaite, Jolita, Zakareviciene, Dalia, Lauzikiene, Mindaugas, Silkunas, Rasa Aurelija, Vankeviciute, Brigita, Vaigauskaite, Grazina, Drasutiene, Irena, Dumalakiene   +9 more
openaire   +2 more sources

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source