Results 41 to 50 of about 132,868 (270)

Fetal inflammation induces acute immune tolerance in the neonatal rat hippocampus

Journal of Neuroinflammation, 2021
Background Infants born preterm due to chorioamnionitis are frequently affected by a fetal inflammatory response syndrome (FIRS) and then by subsequent postnatal infections. FIRS and postnatal systemic inflammatory events independently contribute to poor
Garima Singh, Bradley J. Segura, Michael K. Georgieff, Tate Gisslen   +3 more
doaj   +1 more source

Prone position in pregnant woman with major burns with severe ARDS on mechanical ventilation

Journal of Mechanical Ventilation, 2023
Burns are skin lesions determined by the thermal energy of heat transfer with cellular protein denaturation. Although infrequent during pregnancy, they can be fatal for both the mother and fetus.
Claudio Luciano Franck
doaj   +1 more source

Examination of the inflammatory nature of different placental syncytiotrophoblast microparticles (STBM) preparations on human monocytes [PDF]

, 2009
Background: Healthy human pregnancies are accompanied by a mild systemic maternal inflammatory response, which includes activation of peripheral blood monocytes.
Messerli, Marianne Simone
core   +1 more source

The Consequences of Chorioamnionitis: Preterm Birth and Effects on Development

Journal of Pregnancy, 2013
Preterm birth is a major cause of perinatal mortality and long-term morbidity. Chorioamnionitis is a common cause of preterm birth. Clinical chorioamnionitis, characterised by maternal fever, leukocytosis, tachycardia, uterine tenderness, and preterm ...
Robert Galinsky, Graeme R. Polglase, Stuart B. Hooper, M. Jane Black, Timothy J. M. Moss   +4 more
doaj   +1 more source

Amniotic fluid interleukin-6 and neutrophil gelatinase-associated lipocalin for predicting fetal inflammatory response syndrome based on histological chorioamnionitis and funisitis

Taiwanese Journal of Obstetrics & Gynecology, 2023
Objective: We aimed to analyze the predictive efficacy of amniotic fluid interleukin-6 (IL-6) and neutrophil gelatinase-associated lipocalin (NGAL) for fetal inflammatory response syndrome (FIRS)-related infection.
Daisuke Katsura, Shunichiro Tsuji, Kaori Hayashi, Shinsuke Tokoro, Takako Hoshiyama, Nobuyuki Kita, Takashi Murakami   +6 more
doaj   +1 more source

Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans: a systematic review [PDF]

, 2009
BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
Pryce, C R, Meinlschmidt, G., Meinlschmidt, M, Tegethoff, M., Pryce, C., Tegethoff, M, Christopher Pryce, Gunther Meinlschmidt, Marion Tegethoff   +8 more
core   +1 more source

C4d Deposition in Fetal Vessels of the Placenta in Neonatal Lupus Syndrome

Case Reports in Obstetrics and Gynecology, 2019
Neonatal lupus syndrome (NLS) is a rare, passively acquired autoimmune syndrome caused by maternal autoantibodies. We describe a case of a newborn with NLS and the accompanying placental findings.
Yuichiro Sato, Tomoko Yamaguchi, Jyunsuke Muraoka, Hajime Taniguchi, Atsushi Kisanuki, Kazunari Maekawa, Atushi Yamashita, Murasaki Aman, Yuki Kodama, Hiroshi Sameshima, Yujiro Asada   +10 more
doaj   +1 more source

Intra-Amniotic Infection with Ureaplasma parvum Causes Preterm Birth and Neonatal Mortality That Are Prevented by Treatment with Clarithromycin

mBio, 2020
Intra-amniotic infection is strongly associated with adverse pregnancy and neonatal outcomes. Most intra-amniotic infections are due to Ureaplasma species; however, the pathogenic potency of these genital mycoplasmas to induce preterm birth is still ...
Kenichiro Motomura, Roberto Romero, Yi Xu, Kevin R. Theis, Jose Galaz, Andrew D. Winters, Rebecca Slutsky, Valeria Garcia-Flores, Chengrui Zou, Dustyn Levenson, Robert Para, Madison M. Ahmad, Derek Miller, Chaur-Dong Hsu, Nardhy Gomez-Lopez   +14 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source