Results 21 to 30 of about 135,029 (235)

Gene expression profile of endotoxin-stimulated leukocytes of the term new born: control of cytokine gene expression by interleukin-10. [PDF]

PLoS ONE, 2013
Increasing evidence now supports the association between the fetal inflammatory response syndrome (FIRS) with the pathogenesis of preterm labor, intraventricular hemorrhage and bronchopulmonary dysplasia.
Dennis Davidson, Alla Zaytseva, Veronika Miskolci, Susana Castro-Alcaraz, Ivana Vancurova, Hardik Patel   +5 more
doaj   +1 more source

Intrauterine activation of the fetal immune system in response to maternal COVID-19

Акушерство, гинекология и репродукция, 2023
Introduction. During pregnancy COVID-19 poses a serious threat to both maternal health and health of paired unborn child. Pregnant women have a high probability of complications due to respiratory viral infections followed by developing critical ...
N. R. Gashimova, L. L. Pankratyeva, V. O. Bitsadze, J. Kh. Khizroeva, N. A. Makatsariya, M. V. Tretyakova, A. S. Shkoda, K. N. Grigoreva, V. I. Tsibizova, J.-C. Gris, F. E. Yakubova, D. V. Blinov, A. D. Makatsariya   +12 more
doaj   +1 more source

Fetal Inflammatory Response Syndrome Associated With Maternal SARS-CoV-2 Infection [PDF]

Pediatrics, 2021
Amid the coronavirus disease 2019 pandemic, uncertainty exists about the potential for vertical transmission from mothers infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to the fetus in utero. In this case report, we aim to demonstrate the occurrence of a fetal inflammatory response syndrome associated with maternal SARS-CoV ...
Kyra L, McCarty, Megan, Tucker, Gene, Lee, Vishal, Pandey   +3 more
openaire   +2 more sources

Targeting Toll‐like receptor‐4 to tackle preterm birth and fetal inflammatory injury

Clinical & Translational Immunology, 2020
Every year, 15 million pregnancies end prematurely, resulting in more than 1 million infant deaths and long‐term health consequences for many children.
Sarah A Robertson, Mark R Hutchinson, Kenner C Rice, Peck‐Yin Chin, Lachlan M Moldenhauer, Michael J Stark, David M Olson, Jeffrey A Keelan   +7 more
doaj   +1 more source

Expression of S100A Alarmins in Cord Blood Monocytes Is Highly Associated With Chorioamnionitis and Fetal Inflammation in Preterm Infants

Frontiers in Immunology, 2020
Background: Preterm infants exposed to chorioamnionitis and with a fetal inflammatory response are at risk for neonatal morbidity and adverse outcome.
Veronika Golubinskaya, Henri Puttonen, Ing-Marie Fyhr, Halfdan Rydbeck, Ann Hellström, Bo Jacobsson, Bo Jacobsson, Bo Jacobsson, Holger Nilsson, Carina Mallard, Karin Sävman, Karin Sävman   +11 more
doaj   +1 more source

A Translational Perspective of Maternal Immune Activation by SARS-CoV-2 on the Potential Prenatal Origin of Neurodevelopmental Disorders: The Role of the Cholinergic Anti-inflammatory Pathway

Frontiers in Psychology, 2021
The emergent Coronavirus Disease 2019 (COVID-19) caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) could produce a maternal immune activation (MIA) via the inflammatory response during gestation that may impair fetal ...
José Javier Reyes-Lagos, Eric Alonso Abarca-Castro, Juan Carlos Echeverría, Hugo Mendieta-Zerón, Hugo Mendieta-Zerón, Alejandra Vargas-Caraveo, Gustavo Pacheco-López   +6 more
doaj   +1 more source

The role of fetal inflammatory response syndrome and fetal anemia in nonpreventable term neonatal encephalopathy [PDF]

Journal of Perinatology, 2016
To evaluate asphyxial patterns in term encephalopathic newborns caused by chorioamnionitis or intrapartum blood loss that resulted in cerebral palsy and allegations of obstetrical professional liability.As an expert witness, JKM identified term newborns with profound neurologic impairment: 18 born in the presence of chorioamnionitis and 14 with ...
J K, Muraskas, A F, Kelly, M S, Nash, J R, Goodman, J C, Morrison   +4 more
openaire   +2 more sources

The use of imaging technology in the assessment of the fetal inflammatory response syndrome—imaging of the fetal thymus [PDF]

Prenatal Diagnosis, 2015
AbstractThe fetal inflammatory response syndrome (FIRS) describes a state of extensive fetal multi organ involvement during chorioamnionitis, and is associated with grave implications on perinatal outcome. The syndrome has been linked to the preterm parturition syndrome and is associated with inflammation/infection processes in most of the fetal organs.
Yael, Sciaky-Tamir, Reli, Hershkovitz, Moshe, Mazor, Ilan, Shelef, Offer, Erez   +4 more
openaire   +2 more sources

Micronutrients and Intrauterine Infection, Preterm Birth and the Fetal Inflammatory Response Syndrome [PDF]

The Journal of Nutrition, 2003
Prematurity is the leading cause of perinatal morbidity and mortality worldwide. Intrauterine infection has emerged as a major cause of premature labor and delivery. It has been estimated that 25% of all preterm deliveries occur to mothers who have microbial invasion of the amniotic cavity, although these infections are mostly subclinical in nature ...
Roberto, Romero, Tinnakorn, Chaiworapongsa, Jimmy, Espinoza   +2 more
openaire   +2 more sources

Fetal inflammation induces acute immune tolerance in the neonatal rat hippocampus

Journal of Neuroinflammation, 2021
Background Infants born preterm due to chorioamnionitis are frequently affected by a fetal inflammatory response syndrome (FIRS) and then by subsequent postnatal infections. FIRS and postnatal systemic inflammatory events independently contribute to poor
Garima Singh, Bradley J. Segura, Michael K. Georgieff, Tate Gisslen   +3 more
doaj   +1 more source