Annals of Hepatology, 2005 Since the excretion of potentially toxic cholephilic organic anions (COAs) produced by the fetus, such as bile acids and biliary pigments, cannot be performed by the fetal liver alone, the placenta and the maternal liver must play a key role ...
José J.G. Marín +4 more
doaj +1 more source
Effects of Maternal Low Protein Diet on Expression of Drug Transporters in the Blood-Brain Barrier of Adult Offspring [PDF]
, 2012 Adverse uterine environment, manifested as low birth weight (LBW), has been shown to predispose individuals to hypertension, diabetes, and obesity by mechanisms that are just beginning to be understood.
Hastings, Bonnie L.
core +1 more source
Fetal membrane imaging and the prediction of preterm birth: a systematic review, current issues, and future directions [PDF]
, 2016 Vanessa Nunes +5 more
openalex +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Reproductive organ on-a-chip technologies and assessments of the fetal-maternal interface
Frontiers in Lab on a Chip TechnologiesIn this review, we discuss recent reproductive organ-on-a-chip (OoC) experiments that encompass multiple target areas of investigation, including model fabrication strategies, transport mechanisms, and immunology.
Hannah A. Richards +4 more
doaj +1 more source
Bacterial isolates from patients with preterm labor with and without preterm rupture of the fetal membranes [PDF]
, 1999 Hiroshige Mikamo +5 more
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Advanced Medical JournalBackground and objectives: Preterm premature rupture of membrane is amniotic fluid leakage due to fetal membrane rupture before 37 gestational weeks. The aim was to know the optimum mode of delivery in pregnant women with preterm premature rupture of ...
Shana Pishtiwan Mohammed Baqi +1 more
doaj +1 more source
Fetal collagenase gene-gene interactions: Is there evidence for amplification of preterm premature rupture of membrane (PPROM) risk? [PDF]
, 2005 Alison G. Cahill +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source