Results 111 to 120 of about 2,436,052 (292)

Molecular bases of the excretion of fetal bile acids and pigments through the fetal liver-placenta-maternal liver pathway

Annals of Hepatology, 2005
Since the excretion of potentially toxic cholephilic organic anions (COAs) produced by the fetus, such as bile acids and biliary pigments, cannot be performed by the fetal liver alone, the placenta and the maternal liver must play a key role ...
José J.G. Marín, Rocio I.R. Macías, Óscar Briz, M.J. Pérez, María Ángeles Serrano   +4 more
doaj   +1 more source

Flow-field mitigation of membrane fouling (FMMF) via manipulation of the convective flow in cross-flow membrane applications

, 2016
Membrane fouling by particulates is largely driven by permeate drag that causes the foulants to move towards the membrane. Cross-flow is used to induce shear at the membrane surface to mitigate the fouling.
Fane, Anthony Gordon, Akhondi, Ebrahim, Krantz, William Bill, Tanudjaja, Henry Jonathan, Zamani, Farhad, Chew, Jia Wei   +5 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Increased fetal insulin receptors and changes in membrane fluidity and lipid composition

, 1982
Fetal tissues exposed to hyperinsulinemia in utero have significantly greater numbers of insulin receptors than do those of controls. We have studied this upregulation phenomenon using crude microsomal membranes from fetal rabbit litters exposed to ...
L. Corbo, N. D. Neufeld
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Pigment epithelial-derived factor in human fetal membranes

, 2017
University of Texas Medical BranchUniversity of Texas Medical Branch at GalvestonObjective: Our main objective was to document, pigment epithelial-derived factor (PEDF), a secreted serine protease inhibitor with anti-angiogenic, anti-inflammatory, and ...
Jossimara Polettini, Menon, Ramkumar, Menon, R., Stalberg, Cecilia,, Nathalia Noda, Noda, Nathalia [UNESP], Jacobsson, Bo,, Noda, N., Stalberg, Cecilia, Bo Jacobson, Noda, Nathalia, Polettini, Jossimara, Cecilia Stalberg, Polettini, J., Jacobson, Bo, Ramkumar Menon, Polettini, Jossimara [UNESP]   +16 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Immunohistochemical expression of collagen type VII antibody in the human fetal temporomandibular joint discs [PDF]

Einstein (São Paulo), 2007
Objective: To study the articular disc morphology and to analyze theimmunohistochemical expression of the type VII collagen marker inhuman fetal temporomandibular joint discs at different gestational ages.Methods: Twenty human fetal temporomandibular ...
Luís Otávio Carvalho de Morais, Fábio Redivo Lodi, Sergio Ricardo Marques, Celina Tizuko Fijiyama Oshima, João Antão Fernandes Júnior, Ricardo Luiz Smith, Luís Garcia Alonso   +6 more
doaj  

Abruptio placentae during fetal myelomeningocele repair

, 2015
Myelomeningocele (MM) is a congenital neural tube defect with serious consequences, including hydrocephaly. An important hope for intrauterine repair is that hydrocephaly may be prevented by reversing the Arnold-Chiari malformation. Three medical centers
Cursino, K, Zambelli, H, Prando, Adilson, Barini, R, Cursino, Kleber, Barreto, MWG, Barini, Ricardo, Sbragia, Lourenço, Sbragia, L, Barreto, Maria Weber G, Prando, A, Zambelli, Herder   +11 more
core   +1 more source