Results 151 to 160 of about 957,134 (321)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Human fetal membranes

, 2015
Biologie cellulaire et ...
openaire   +1 more source

Mutations in fetal genes involved in innate immunity and host defense against microbes increase risk of preterm premature rupture of membranes (PPROM) [PDF]

, 2017
Bhavi P. Modi, María E. Teves, Laurel N. Pearson, Hardik I. Parikh, Hannah Haymond‐Thornburg, John L. Tucker, Piya Chaemsaithong, Nardhy Gomez‐Lopez, Timothy P. York, Roberto Romero, Jerome F. Strauss   +10 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Generation and characterization of human Fetal membrane and Decidual cell lines for reproductive biology experiments†. [PDF]

Biol Reprod, 2022
Radnaa E, Urrabaz-Garza R, Elrod ND, de Castro Silva M, Pyles R, Han A, Menon R.   +6 more
europepmc   +1 more source

Teratogenic test of Pandanus conoideus var. yellow fruit extract to development of rat embryo (Rattus norvegicus) [PDF]

, 2010
Muna L, Astirin OP, Sugiyarto. 2010. Uji teratogenik ekstrak Pandanus conoideus varietas buah kuning terhadap perkembangan embrio tikus putih (Rattus norvegicus). Nusantara Bioscience 2: 126-134.
ASTIRIN, OKID PARAMA, MUNA, LINTAL, SUGIYARTO,   +2 more
core  

The Prediction of Maternal Serum Alpha Fetoprotein Level and Fetal Nuchal Translucency, Forcases Involving Preterm Prelabor Rupture of Membranes [PDF]

, 2021
Yiming Chen, Yijie Chen, Lei Chen, Wenwen Ning, Xiaoying Wang, Zhifen Zhang, Xiaoying Wang, Zhifen Zhang   +7 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Functional role and regulation of permeability-glycoprotein (P-gp) in the fetal membrane during drug transportation. [PDF]

Am J Reprod Immunol, 2022
Kammala A, Benson M, Ganguly E, Richardson L, Menon R.   +4 more
europepmc   +1 more source

Vimentin downregulation is an inherent feature of murine erythropoiesis and occurs independently of lineage [PDF]

, 1990
In mammalian erythropoiesis, the mature cells of the primitive lineage remain nucleated while those of the definitive lineage are anuclear. One of the molecular and structural changes that precedes enucleation in cells of the definitive lineage is the ...
Lazarides, Elias, Sangiorgi, Frank, Woods, Catherine M.   +2 more
core