Results 91 to 100 of about 208,842 (300)

Intrapartum Fetal Heart Rate: A Possible Predictor of Neonatal Acidemia and APGAR Score

Frontiers in Physiology, 2018
Background: Predicting perinatal outcomes based on patterns of fetal heart rate (FHR) remains a challenge. The aim of this study was to evaluate intrapartum FHR variability as predictor for neonatal acidemia and APGAR score.Methods: This was a ...
Thâmila Kamila de Souza Medeiros, Thâmila Kamila de Souza Medeiros, Mirela Dobre, Daniela Monteiro Baptista da Silva, Daniela Monteiro Baptista da Silva, Andrei Brateanu, Ovidiu Constantin Baltatu, Ovidiu Constantin Baltatu, Luciana Aparecida Campos, Luciana Aparecida Campos   +9 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Antenatal Care Bundle for Preventing Stillbirths: Proposed Intervention by Stillbirth Society of India

Indian Journal of Community Medicine
Antenatal Care Bundle” presents evidence-based antenatal care interventions aimed at reducing stillbirths, developed by the Stillbirth Society of India.
Manju Puri, Tamkin Khan, Asna Ashraf, Bharti Sharma, Achla Batra, Amrita Chaurasia, Aradhana Singh, Ayesha Ahmad, Bushra Fatima, Harpreet Kaur, Kiran Pandey, Manisha Kumar, Nuzhat Aziz, Saroj Singh, Seema Chopra, Shrinivas Gadappa, Smriti Agrawal, Neelam Aggarwal   +17 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The use of actograph in the assessment of fetal well-being [PDF]

, 2018
PURPOSE: Third trimester maternal perception of fetal movements is often used to assess fetal well-being. However, its true clinical value is unknown, primarily because of the variability in subjective quantification.
Visser, Gerard HA, Nowlan, Niamh C, Vaidyanathan, Ravi, Lees, Christoph C, Lai, Jonathan   +4 more
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Comparison of advanced electronic intrapartum monitoring system (Keyar device and Daksh application) with standard cardiotocography for assessment of fetal heart rate and uterine contractions

Journal of Family Medicine and Primary Care
Background: Conventional cardiotocography (CTG) used for intrapartum fetal monitoring has limitations related to mobility, comfort, and usability, especially in low-resource settings. Noninvasive ECG-based monitoring devices offer a potential alternative.
Lajya D. Goyal, Balpreet Kaur, Priyanka Singh   +2 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

FIGO consensus guidelines on intrapartum fetal monitoring: Adjunctive technologies [PDF]

, 2015
Ayres-de-Campos, Diogo, FIGO Intrapartum, Fetal Monitoring Expert Consensus Panel, Visser, Gerard H, Surbek, Daniel   +3 more
core   +2 more sources