Results 81 to 90 of about 4,947,559 (270)

Ways of Making Birth Difficult

South African Family Practice, 1990
No abstract available.
G.J. Hofmeyr
doaj   +1 more source

FIGO consensus guidelines on intrapartum fetal monitoring: Introduction

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015
Auscultation of the fetal heart rate (FHR) became part of routine intrapartum care inmany countries during the 19th century [1], and remains an important form of fetal surveillance, particularly in low-risk pregnancies and in low-resource countries ...
D. Ayres-de-Campos, S. Arulkumaran
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Intrapartum Fetal Heart Rate: A Possible Predictor of Neonatal Acidemia and APGAR Score

Frontiers in Physiology, 2018
Background: Predicting perinatal outcomes based on patterns of fetal heart rate (FHR) remains a challenge. The aim of this study was to evaluate intrapartum FHR variability as predictor for neonatal acidemia and APGAR score.Methods: This was a ...
Thâmila Kamila de Souza Medeiros, Thâmila Kamila de Souza Medeiros, Mirela Dobre, Daniela Monteiro Baptista da Silva, Daniela Monteiro Baptista da Silva, Andrei Brateanu, Ovidiu Constantin Baltatu, Ovidiu Constantin Baltatu, Luciana Aparecida Campos, Luciana Aparecida Campos   +9 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Antenatal Care Bundle for Preventing Stillbirths: Proposed Intervention by Stillbirth Society of India

Indian Journal of Community Medicine
Antenatal Care Bundle” presents evidence-based antenatal care interventions aimed at reducing stillbirths, developed by the Stillbirth Society of India.
Manju Puri, Tamkin Khan, Asna Ashraf, Bharti Sharma, Achla Batra, Amrita Chaurasia, Aradhana Singh, Ayesha Ahmad, Bushra Fatima, Harpreet Kaur, Kiran Pandey, Manisha Kumar, Nuzhat Aziz, Saroj Singh, Seema Chopra, Shrinivas Gadappa, Smriti Agrawal, Neelam Aggarwal   +17 more
doaj   +1 more source

FIGO consensus guidelines on intrapartum fetal monitoring: Adjunctive technologies

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015
Cardiotocography (CTG) has a high sensitivity but only a limited specificity in predicting fetal hypoxia/acidosis [1]. In other words, a normal CTG is reassuring regarding the state of fetal oxygenation as hypoxia/acidosis is generally restricted to ...
G. Visser, D. Ayres-de-Campos
semanticscholar   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source