Results 31 to 40 of about 90,146 (293)
Acta Pharmaceutica Sinica B, 2023 Medication during pregnancy is widespread, but there are few reports on its fetal safety. Recent studies suggest that medication during pregnancy can affect fetal morphological and functional development through multiple pathways, multiple organs, and ...
Zhengjie Lu +7 more
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Fetal programming and Wilms tumor [PDF]
Pediatric Blood & Cancer, 2018 AbstractBackgroundThe “fetal programming” hypothesis has been evaluated in many adult diseases including cancer, but not for Wilms tumor. Wilms tumor has been related to high birthweight, but little is known about other growth metrics such as a baby's birth length, ponderal index, or placenta size, which can shed additional light on growth patterns ...
Julia E. Heck +6 more
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Medical alphabet, 2019 The concept of fetal programming implies the influence of factors of the external and internal environment in the intrauterine period on the epigenetic regulation of the genome, which leads to phenotypic changes in the fetus, as well as to postnatal diseases of man, manifesting throughout life. It is possible to improve the state of health, quality and
E. A. Sandakova, I. G. Zhukovskaya
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Maternal Mineral Nutrition Regulates Fetal Genomic Programming in Cattle: A Review
Metabolites, 2023 Maternal mineral nutrition during the critical phases of fetal development may leave lifetime impacts on the productivity of an individual. Most research within the developmental origins of the health and disease (DOHaD) field is focused on the role of ...
Muhammad Anas +6 more
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Maternal obesity has little effect on the immediate offspring but impacts on the next generation [PDF]
, 2013 Maternal obesity during pregnancy has been linked to an increased risk of obesity and cardiometabolic disease in the offspring, a phenomenon attributed to developmental programming. Programming effects may be transmissible across generations through both
Dakin, Rachel S. +7 more
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PLoS ONE, 2019 Biochemical changes in utero may alter normal fetal development, resulting in disease later in life, a phenomenon known as fetal programming. Recent epidemiological studies link fetal programming to negative health outcomes, such as low birth weight and ...
Sandhya Khurana +6 more
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Adipose tissue and fetal programming [PDF]
Diabetologia, 2012 Adipose tissue function changes with development. In the newborn, brown adipose tissue (BAT) is essential for ensuring effective adaptation to the extrauterine environment, and its growth during gestation is largely dependent on glucose supply from the mother to the fetus.
M E, Symonds +3 more
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Timing of maternal exposure and fetal sex determine the effects of low-level chemical mixture exposure on the fetal neuroendocrine system in sheep [PDF]
, 2016 We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary ...
Bellingham, M. +7 more
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Can Thrifty Gene(s) or Predictive Fetal Programming for Thriftiness Lead to Obesity?
Journal of Obesity, 2011 Obesity and related disorders are thought to have their roots in metabolic “thriftiness” that evolved to combat periodic starvation. The association of low birth weight with obesity in later life caused a shift in the concept from thrifty gene to thrifty
Ulfat Baig +3 more
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Maternal Diabetes and Fetal Programming Toward Neurological Diseases: Beyond Neural Tube Defects
Frontiers in Endocrinology, 2018 The purpose of this review was to search for experimental or clinical evidence on the effect of hyperglycemia in fetal programming to neurological diseases, excluding evident neural tube defects. The lack of timely diagnosis and the inadequate control of
Berenice Márquez-Valadez +6 more
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