Results 11 to 20 of about 90,146 (293)

Transcriptome and morphological analysis on the heart in gestational protein-restricted aging male rat offspring

open access: yesFrontiers in Cell and Developmental Biology, 2022
Background: Adverse factors that influence embryo/fetal development are correlated with increased risk of cardiovascular disease (CVD), type-2 diabetes, arterial hypertension, obesity, insulin resistance, impaired kidney development, psychiatric ...
Marina S. Folguieri   +4 more
doaj   +1 more source

Gestational Low Protein Diet Modulation on miRNA Transcriptome and Its Target During Fetal and Breastfeeding Nephrogenesis

open access: yesFrontiers in Physiology, 2021
BackgroundThe kidney ontogenesis is the most structurally affected by gestational protein restriction, reducing 28% of their functional units. The reduced nephron number is predictive of hypertension and cardiovascular dysfunctions that are generally ...
Letícia de Barros Sene   +5 more
doaj   +1 more source

Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys. [PDF]

open access: yes, 2014
Polycystic ovary syndrome (PCOS) is prevalent in reproductive-aged women and confounded by metabolic morbidities, including insulin resistance and type 2 diabetes.
Abbott, David H   +5 more
core   +11 more sources

Long-Term Consequences of Adaptive Fetal Programming in Ruminant Livestock

open access: yesFrontiers in Animal Science, 2022
Environmental perturbations during gestation can alter fetal development and postnatal animal performance. In humans, intrauterine growth restriction (IUGR) resulting from adaptive fetal programming is known as a leading cause of perinatal morbidity and ...
Allison N. Vautier, Caitlin N. Cadaret
doaj   +1 more source

The mother and the young child: Who programs whom [PDF]

open access: yesRomanian Journal of Pediatrics, 2020
Intrauterine life is regulated by an epigenetic programme which adapts fetal life to the current and presumed conditions. The fetal programming determined by maternal nutritional disorders is at the origin of some metabolic and cardiovascular diseases of
Sorin Buzinschi
doaj   +1 more source

Relative validity of a web-based food frequency questionnaire for Danish adolescents

open access: yesNutrition Journal, 2018
Background With increased focus on dietary intake among youth and risk of diseases later in life, it is of importance, prior to assessing diet-disease relationships, to examine the validity of the dietary assessment tool.
Anne A. Bjerregaard   +4 more
doaj   +1 more source

The Impact of Nutrient Intake and Metabolic Wastes during Pregnancy on Offspring Hypertension: Challenges and Future Opportunities

open access: yesMetabolites, 2023
Hypertension can have its origin in early life. During pregnancy, many metabolic alterations occur in the mother that have a crucial role in fetal development.
You-Lin Tain, Chien-Ning Hsu
doaj   +1 more source

Evolution of Thriftiness: An analytical viewpoint [PDF]

open access: yes, 2008
We examine here, using a simple mathematical model, the conditions under which thrifty genes or fetal programming could evolve. Obesity and related disorders are thought to have their roots in metabolic thirftiness that evolved to combat periodic ...
Milind Watve, Prajakta Belsare
core   +2 more sources

Reproducibility of a web-based FFQ for 13- to 15-year-old Danish adolescents

open access: yesJournal of Nutritional Science, 2016
FFQ are widely used in large-scale studies to assess dietary intake. To aid interpretation of diet–disease associations assessment of validity must be performed.
Anne A. Bjerregaard   +3 more
doaj   +1 more source

Corticotropin-releasing hormone as the homeostatic rheostat of feto-maternal symbiosis and developmental programming In utero and neonatal life [PDF]

open access: yes, 2017
A balanced interaction between the homeostatic mechanisms of mother and the devel- oping organism during pregnancy and in early neonatal life is essential in order to ensure optimal fetal development, ability to respond to various external and internal ...
Alcantara-Alonso   +114 more
core   +3 more sources

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