Epigenetic Programming and Fetal Metabolic Programming
Frontiers in Endocrinology, 2019 Fetal metabolic programming caused by the adverse intrauterine environment can induce metabolic syndrome in adult offspring. Adverse intrauterine environment introduces fetal long-term relatively irreversible changes in organs and metabolism, and thus ...
Ziqiang Zhu +3 more
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Oxidative Stress Mediates the Fetal Programming of Hypertension by Glucocorticoids. [PDF]
Antioxidants (Basel), 2021 The field of cardiovascular fetal programming has emphasized the importance of the uterine environment on postnatal cardiovascular health. Studies have linked increased fetal glucocorticoid exposure, either from exogenous sources (such as dexamethasone ...
Lamothe J +8 more
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Fetal Programming and Fetal Psychology [PDF]
Infant and Child Development, 2011 The introduction of the ‘fetal programming hypothesis’, first in epidemiology, subsequently in a broad range of disciplines concerned with developmental biology, has generated new interest in phenotypic plasticity, the mechanisms that govern it, and its ...
Ellison, Peter T.
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Maternal Overnutrition and Fetal Programming: Long-Term Metabolic, Cognitive, and Epigenetic Consequences. [PDF]
CellsMaternal nutrition during pregnancy critically influences fetal programming, shaping the offspring’s lifelong health and disease susceptibility. Both undernutrition and overnutrition affect fetal metabolism, predisposing offspring to obesity and ...
Schiera G +7 more
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Paternal effects on fetal programming. [PDF]
Anim Reprod, 2023 Paternal programming is the concept that the environmental signals from the sire's experiences leading up to mating can alter semen and ultimately affect the phenotype of resulting offspring. Potential mechanisms carrying the paternal effects to offspring can be associated with epigenetic signatures (DNA methylation, histone modification and non-coding
Dahlen CR +5 more
europepmc +4 more sources
Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR [PDF]
Frontiers in Endocrinology, 2019 Intrauterine growth restriction (IUGR) is a condition whereby a fetus is unable to achieve its genetically determined potential size. IUGR is a global health challenge due to high mortality and morbidity amongst affected neonates.
Dechend, Ralf +6 more
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Fetal programming: could intrauterin life affect health status in adulthood? [PDF]
Obstet Gynecol Sci, 2021 Intrauterine life is one of the most important periods of life. As the development of the fetus continues, the mechanisms that affect adult health also begin to mature.
Öztürk HNO, Türker PF.
europepmc +2 more sources
Fetal programming and vascular dysfunction
Artery Research, 2017 Cardiovascular diseases are the main cause of mortality and morbidity in Western countries, but the underlying mechanisms are still poorly understood.
T.A. Meister +4 more
doaj +4 more sources
Transcriptome analysis of umbilical cord mesenchymal stem cells revealed fetal programming due to chorioamnionitis. [PDF]
Sci Rep, 2022 Although chorioamnionitis (CAM) has been demonstrated to be associated with numerous short- and long-term morbidities, the precise mechanisms remain unclear.
Noguchi Y +12 more
europepmc +2 more sources
A combination analysis based on bioinformatics tools reveals new signature genes related to maternal obesity and fetal programming. [PDF]
Front Med (Lausanne)BackgroundMaternal obesity significantly influences fetal development and health later in life; however, the molecular mechanisms behind it remain unclear.
Liu C +6 more
europepmc +2 more sources