Results 11 to 20 of about 1,024,043 (307)

Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat [PDF]

, 2002
Earlier studies at our laboratory indicated that several hydroxylated polychlorinated biphenyls (OH-PCBs) detected in human blood could specifically inhibit thyroxine (T4) transport by competitive binding to the thyroid hormone transport protein ...
Assink, Y., Berg, J.H.J. van den, Bergman, A., Brouwer, A., Cenijn, P.H., Koeman, J.H., Meerts, I.A.T.M., Weijers, B.M.   +7 more
core   +8 more sources

In heart failure reactivation of RNA-binding proteins is associated with the expression of 1,523 fetal-specific isoforms.

PLoS Computational Biology, 2022
Reactivation of fetal-specific genes and isoforms occurs during heart failure. However, the underlying molecular mechanisms and the extent to which the fetal program switch occurs remains unclear.
Matteo D'Antonio, Jennifer P Nguyen, Timothy D Arthur, Hiroko Matsui, Margaret K R Donovan, Agnieszka D'Antonio-Chronowska, Kelly A Frazer   +6 more
doaj   +1 more source

Association of a MET genetic variant with autism-associated maternal autoantibodies to fetal brain proteins and cytokine expression. [PDF]

, 2011
The contribution of peripheral immunity to autism spectrum disorders (ASDs) risk is debated and poorly understood. Some mothers of children with ASD have autoantibodies that react to fetal brain proteins, raising the possibility that a subset of ASD ...
Ashwood, P, Braunschweig, D, Campbell, DB, Heuer, L, Van de Water, J   +4 more
core   +2 more sources

Tissue engineering a fetal membrane [PDF]

, 2011
The aim of this study was to construct an artificial fetal membrane (FM) by combination of human amniotic epithelial stem cells (hAESCs) and a mechanically enhanced collagen scaffold containing encapsulated human amniotic stromal fibroblasts (hASFs ...
Adam M. Squires, Anna L. David, Bipasha Chowdhury, Che John Connon, Connon C.J., Grinnell F., Ian William Hamley, Jones R.R., Kirkham S.M., Roanne Razalia Jones, Shengli Mi, Trinkaus R.V.   +11 more
core   +1 more source

Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model

Disease Models & Mechanisms, 2018
Osteoarthritis (OA), a degenerative joint disease characterized by progressive cartilage degeneration, is one of the leading causes of disability worldwide owing to the limited regenerative capacity of adult articular cartilage.
Iris Ribitsch, Rupert L. Mayer, Monika Egerbacher, Simone Gabner, Maciej M. Kańduła, Julie Rosser, Eva Haltmayer, Ulrike Auer, Sinan Gültekin, Johann Huber, Andrea Bileck, David P. Kreil, Christopher Gerner, Florien Jenner   +13 more
doaj   +1 more source

Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum. [PDF]

, 2018
BACKGROUND: The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection.
Abraham, David, Bennuru, Sasisekhar, Eberhard, Mark L., Hess Ligas, Jessica A., Lustigman, Sara, Nutman, Thomas B., Patton, John B., Torigian, April R.   +7 more
core   +3 more sources

Proteomic analysis of adipose tissue during the last weeks of gestation in pure and crossbred Large White or Meishan fetuses gestated by sows of either breed

Journal of Animal Science and Biotechnology, 2018
Background The degree of adipose tissue development at birth may influence neonatal survival and subsequent health outcomes. Despite their lower birth weights, piglets from Meishan sows (a fat breed with excellent maternal ability) have a higher survival
F. Gondret, B. Guével, M. C. Père, H. Quesnel, Y. Billon, E. Com, L. Canario, I. Louveau, L. Liaubet   +8 more
doaj   +1 more source

Maternal PlGF and umbilical Dopplers predict pregnancy outcomes at diagnosis of early-onset fetal growth restriction

The Journal of Clinical Investigation, 2023
BACKGROUND Severe, early-onset fetal growth restriction (FGR) causes significant fetal and neonatal mortality and morbidity. Predicting the outcome of affected pregnancies at the time of diagnosis is difficult, thus preventing accurate patient counseling.
Rebecca Spencer, Kasia Maksym, Kurt Hecher, Karel Maršál, Francesc Figueras, Gareth Ambler, Harry Whitwell, Nuno Rocha Nené, Neil J. Sebire, Stefan R. Hansson, Anke Diemert, Jana Brodszki, Eduard Gratacós, Yuval Ginsberg, Tal Weissbach, Donald M. Peebles, Ian Zachary, Neil Marlow, Angela Huertas-Ceballos, Anna L. David   +19 more
doaj   +1 more source

Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation. [PDF]

, 2017
Advances in genomic profiling present new challenges of explaining how changes in DNA and RNA are translated into proteins linking genotype to phenotype.
Cao, Hui, Chandel, Navdeep S, DeBerardinis, Ralph J, Dickerson, Kathryn E, Gu, Zhimin, Hu, Zeping, Li, Dan, Li, Mushan, Liu, Xin, Ni, Min, Shao, Zhen, Signer, Robert AJ, Weinberg, Samuel E, Xu, Jian, Zhang, Yuannyu, Zhou, Feng   +15 more
core   +1 more source

Convergent evolution of pregnancy-specific glycoproteins in human and horse [PDF]

, 2016
Pregnancy-specific glycoproteins (PSGs) are members of the carcinoembryonic antigen cell adhesion molecule (CEACAM) family that are secreted by trophoblast cells. PSGs may modulate immune, angiogenic and platelet responses during pregnancy.
Amanda M de Mestre, Baker, Denis Aleksic, Donaldson, Fialova, Jana Hänske, Johannes Handler, Jordan E Read, Lisa Blaschke, Robert Kammerer, Ronan O’Riordan, Schumacher, Sophie Mißbach, Tom Moore, Victoria Cabrera-Sharp, Wiebke Weiß, Wolfgang Zimmermann   +16 more
core   +2 more sources