Results 1 to 10 of about 5,507,050 (377)

Pulmonary Hypoplasia Caused by Fetal Ascites in Congenital Cytomegalovirus Infection Despite Fetal Therapy [PDF]

Frontiers in Pediatrics, 2017
We report two cases of pulmonary hypoplasia due to fetal ascites in symptomatic congenital cytomegalovirus (CMV) infections despite fetal therapy. The patients died soon after birth. The pathogenesis of pulmonary hypoplasia in our cases might be thoracic
Kazumichi Fujioka, Ichiro Morioka, Kosuke Nishida, Mayumi Morizane, Kenji Tanimura, Masashi Deguchi, Kazumoto Iijima, Hideto Yamada   +7 more
doaj   +3 more sources

Trends in research related to fetal therapy from 2012 to 2022: a bibliometric analysis [PDF]

Frontiers in Pediatrics, 2023
BackgroundThe development of prenatal diagnosis technology allows prompt detection of severe fetal diseases. To address adverse factors that threaten fetal survival, fetal therapy came into existence, which aims to preserve the function after birth to a ...
Yang Jia, Xiaoling Liang, Lini Liu, Huixi Ma, Chenhao Xu, Jingyuan Zeng, Rong Xu, Lu Ye, Linjun Xie   +8 more
doaj   +2 more sources

Fetal gene therapy

Journal of Inherited Metabolic Disease, 2023
AbstractFetal gene therapy was first proposed toward the end of the 1990s when the field of gene therapy was, to quote the Gartner hype cycle, at its “peak of inflated expectations.” Gene therapy was still an immature field but over the ensuing decade, it matured and is now a clinical and market reality.
Simon N. Waddington, William H. Peranteau, Ahad A. Rahim, Ashley K. Boyle, Manju A. Kurian, Paul Gissen, Jerry K. Y. Chan, Anna L. David   +7 more
openaire   +5 more sources

Gestational age and Quintero staging as predictors of single fetal demise in twin-twin transfusion syndrome after fetoscopic laser photocoagulation: a systematic review and meta-analysisAJOG Global Reports at a Glance

AJOG Global Reports, 2022
BACKGROUND: Single fetal demise after intervention for twin-twin transfusion syndrome is a relatively common complication and is often devastating for the patients.
Ahmed A. Nassr, MD, PhD, Kamran Hessami, MD, Jimmy Espinoza, MD, Roopali Donepudi, MD, Magdalena Sanz Cortes, MD, PhD, Michael A. Belfort, MD, PhD, Alireza A. Shamshirsaz, MD   +6 more
doaj   +1 more source

Reference values for fetal Doppler-based cardiocirculatory indices in monochorionic-diamniotic twin pregnancy

BMC Pregnancy and Childbirth, 2021
Background Placental anastomoses in monochorionic diamniotic (MCDA) twin pregnancy have a major impact on fetal circulation. This study was designed to define reference ranges of cardiac and vascular Doppler indices in MCDA twin pregnancies. Methods This
Thananan Chongsomboonsuk, Nisarat Phithakwatchara, Katika Nawapun, Sommai Viboonchart, Suparat Jaingam, Tuangsit Wataganara   +5 more
doaj   +1 more source

Metabolomics in Prenatal Medicine: A Review

Frontiers in Medicine, 2021
Pregnancy is a complicated and insidious state with various aspects to consider, including the well-being of the mother and child. Developing better non-invasive tests that cover a broader range of disorders with lower false-positive rates is a ...
Giovanni Monni, Luigi Atzori, Valentina Corda, Francesca Dessolis, Ambra Iuculano, K. Joseph Hurt, Federica Murgia, Federica Murgia   +7 more
doaj   +1 more source

Non-immune fetal hydrops: etiology and outcome according to gestational age at diagnosis. [PDF]

, 2020
OBJECTIVE: Fetal hydrops is associated with increased perinatal morbidity and mortality. The etiology and outcome of fetal hydrops may differ according to the gestational age at diagnosis.
A. Bhide, A. Khalil, A. Kulkarni, B. Thilaganathan, E. Dempsey, F. G. Sileo, Hutchison AA, I. Branescu, Jauniaux E, Norton ME, S. Mansour, Santolaya J, T. Homfray   +12 more
core   +2 more sources

Autologous bone marrow-derived MSCs engineered to express oFVIII-FLAG engraft in adult sheep and produce an effective increase in plasma FVIII levels

Frontiers in Immunology, 2022
IntroductionHemophilia A (HA) is the most common X-linked bleeding disorder, occurring in 1 in 5,000 live male births and affecting >1 million individuals worldwide.
Brady Trevisan, Martin Rodriguez, Hailey Medder, Shannon Lankford, Rebecca Combs, John Owen, Anthony Atala, Christopher D. Porada, Graça Almeida-Porada   +8 more
doaj   +1 more source

Fetal therapies as standard prenatal care in Japan [PDF]

Obstetrics & Gynecology Science, 2020
With recent advances in fetal medicine, various attempts have been made to save fetuses facing perinatal death or devastating consequences despite optimal management after birth.
Haruhiko Sago, Seiji Wada
doaj   +1 more source

Perinatal Gene Transfer to the Liver [PDF]

, 2011
The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM, Chan, JK, Howe, SJ, McKay, TR, Rahim, AA, Waddington, SN, Ward, NJ   +6 more
core   +1 more source