North American Fetal Therapy Network: Maternal Outcomes in Fetal Aqueductal Stenosis. [PDF]
Fetal Diagn TherINTRODUCTION: Fetal aqueductal stenosis (AS) affects approximately 1:1,000 pregnancies. Obstruction of cerebral spinal fluid circulation occurs at the aqueduct of Sylvius, leading to progressive hydrocephalus and macrocephaly, which often necessitates ...
Emery SP +13 more
europepmc +2 more sources
FIGO consensus guidelines on intrapartum fetal monitoring: Cardiotocography [PDF]
, 2015 Intermittent auscultation is the technique used to listen to the fetal heart rate (FHR) for short periods of time without a display of the resulting pattern.
Chandraharan, Edwin +15 more
core +2 more sources
Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans: a systematic review [PDF]
, 2009 BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
Pryce, C R +8 more
core +1 more source
Ontological Differences in First Compared to Third Trimester Human Fetal Placental Chorionic Stem Cells [PDF]
, 2012 Human mesenchymal stromal/stem cells (MSC) isolated from fetal tissues hold promise for use in tissue engineering applications and cell-based therapies, but their collection is restricted ethically and technically.
Vanleene, Maximilien +55 more
core +1 more source
A closer look at discordant placental echogenicity: two cases under the microscope
Clinical Case Reports, 2021 Discordant placental echogenicity is observed in MC pregnancies complicated with twin anemia‐polycythemia sequence, but could also belong to complicated singleton gestation.
Mariano M. Lanna +6 more
doaj +1 more source
Color Doppler Score: A New Approach for Monitoring a Large Placental Chorioangioma
Case Reports in Obstetrics and Gynecology, 2014 We employed color Doppler score as an innovative approach for the prenatal diagnosis and monitoring of a large placental chorioangioma case diagnosed at 26 weeks and the subjective semiquantitative assessment of the vascularization.
Maria Angelica Zoppi +7 more
doaj +1 more source
Defining the Optimal FVIII Transgene for Placental Cell-Based Gene Therapy to Treat Hemophilia A
Molecular Therapy: Methods & Clinical Development, 2020 The delivery of factor VIII (FVIII) through gene and/or cellular platforms has emerged as a promising hemophilia A treatment. Herein, we investigated the suitability of human placental cells (PLCs) as delivery vehicles for FVIII and determined an optimal
Nadia El-Akabawy +14 more
doaj +1 more source
The Fetal Heart in Twin-to-Twin Transfusion Syndrome
International Journal of Pediatrics, 2010 Twin-to-twin transfusion syndrome is a severe complication occurring in 10% of monochorionic twin pregnancies. The disease is usually explained as due to an intrauterine imbalance in intertwin blood exchange, which leads to a volume depleted-donor twin ...
Tim Van Mieghem +6 more
doaj +1 more source
Taiwanese Journal of Obstetrics & Gynecology, 2010 Objective: Safely targeting the fetal gastrointestinal tract during early gestation is essential to develop effective prenatal gene therapy for gastrointestinal diseases.
Anna L. David +8 more
doaj +1 more source
Seminal Fluid Metabolomic Markers of Oligozoospermic Infertility in Humans
Metabolites, 2020 Infertility affects 12−15% of couples worldwide, and male factors are the cause of nearly half of all cases. Studying seminal fluid composition could lead to additional diagnostic accuracy and a better understanding of the pathophysiology of male ...
Federica Murgia +9 more
doaj +1 more source