Results 81 to 90 of about 516,032 (299)

Alternativas de manejo expectante de la rotura prematura de membranas antes de la viabilidad en embarazos únicos

Revista Chilena de Obstetricia y Ginecología, 2012
La rotura prematura de membranas (RPM) antes de la viabilidad fetal constituye una complicación obstétrica de baja incidencia, pero que se asocia a una alta morbimortalidad materna y perinatal.
Adriana Doren V, Jorge Carvajal C
doaj  

Antimicrobial efficacy against Pseudomonas aeruginosa biofilm formation in a three-dimensional lung epithelial model and the influence of fetal bovine serum [PDF]

, 2017
In vitro models that mimic in vivo host-pathogen interactions are needed to evaluate candidate drugs that inhibit bacterial virulence traits. We established a new approach to study Pseudomonas aeruginosa biofilm susceptibility on biotic surfaces, using a
Coenye, Tom, Crabbé, Aurélie, Davis, Richard, De La Fuente-Nùñez, César, Hancock, Robert EW, Ledesma, Maria A, Liu, Yulong, Matthijs, Nele, Nickerson, Cheryl A., Rigole, Petra, Sarker, Shameema, Van Houdt, Rob   +11 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Causes of sheep dystocia in Djelfa area (Algeria)

Revue Marocaine des Sciences Agronomiques et Vétérinaires, 2019
The objective of this study was to clarify the most common causes of sheep dystocia in Djelfa area (Algeria). 87 ewes suffering from dystocia were investigated in this study. Dystocia was diagnosed after careful vaginal examination.
Elchikh MOSTEFAI, Mokhtaria KOUIDRI, Sidi Mohammed Ammar SELLES   +2 more
doaj   +2 more sources

Effects of Trehalose and Fetal Bovine Serum on Cryopreservation of HBL-100 Human Breast Cells

Zhileng xuebao, 2017
Establishing a high-quality biobank is very important, but the cryoprotective agent (CPA) type and concentration have a considerable influence on the cryopreservation effect.
Wang Meixia, Liang Wei, Ye Ping, Liu Baolin   +3 more
doaj  

Population Kinetics and Protein Profiles of Co-Cultured Adult and Fetus Rabbit Bladder Smooth Muscle Cells

Urology Research and Practice
Objective: Bladder tissue models have been developed using smooth muscle cells (SMCs) on various scaffolds to mimic bladder morphology and physiology.
Hayrunisa Kahraman Esen, Burcu Biltekin, Mevlit Korkmaz, B. Haluk Güvenç   +3 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Ultrasonographic Assessment of Fetal Viability in Pregnant Women with First-Trimester Bleeding at Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria

International Journal of Medicine and Health Development
Background: Vaginal bleeding in the first trimester is a fairly common problem, which may be associated with lower abdominal pain. It varies from spotting to a life-threatening event of active profuse bleeding.
Chisolum O. Okafor, Odira C. Anajuba, Chinekwu S. Nwosu, Charles I. Okafor, Munachi O. Nwabunike, Ifeanyi O. Uzukwu, Ugochukwu A. Aguwamba, Kelechi U. Okoye, Adaobi C. Emegoakor   +8 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source