Results 41 to 50 of about 486,329 (260)
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Objective To investigate the factors associated with late stillbirth among women with hypertensive disorders of pregnancy (HDP). Material and Methods The clinical details of women with HDP having late stillbirth were compared with controls having ...
Manisha Kumar +3 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The position of the testis during the fetal period: an additional parameter to estimate fetal weight
PURPOSE: To establish a correlation between testicular position and fetal weight, in order to provide an additional prenatal parameter for fetal weight estimation. MATERIALS AND METHODS: We studied 288 testes from 144 human fetuses.
Luciano A. Favorito +2 more
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
EFFECT OF BIRTH WEIGHT ON SUCCESS OF VAGINAL BIRTH AFTER CAESAREAN DELIVERY
Background: There is widespread concern about increasing proportion of births by caesarean section. Many factors can affect the likelihood of success of vaginal birth after caesarean section.
Sadia Anwar +3 more
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Effect of Routine Antenatal Daily Iron Supplementation on Fetal Weight
Background: To study the effect of routine antenatal daily iron supplementation on fetal weight. Methods: In this randomized control trial thirty two adult female and ten adult male Sprague- Dawley rats (weighing 200-250 gm) were taken.
Umbreen Noor
doaj
Introduction: Assessment of fetal weight is a vital factor in antenatal care, not only in the management of labor and delivery but also in identifying fetal weight disorders.
Raziyeh Mossayebnezhad +3 more
doaj

