Results 51 to 60 of about 2,766,339 (297)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Maternal psychosocial stress during pregnancy and placenta weight: evidence from a national cohort study [PDF]
, 2010 To study in a large-scale cohort with prospective data the associations between psychosocial stress during pregnancy and placenta weight at birth. Animal data suggest that the placenta is involved in stress-related fetal programming.; We defined a priori
Andrea H Meyer +16 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Cellular and hormonal disruption of fetal testis development in sheep reared on pasture treated with sewage sludge [PDF]
, 2005 The purpose of this study was to evaluate whether experimental exposure of pregnant sheep to a mixture of environmental chemicals added to pasture as sewage sludge (n = 9 treated animals) exerted effects on fetal testis development or function ...
Paul, Catriona +11 more
core +1 more source
Hypertension in Pregnancy, 2020 Objective To investigate the factors associated with late stillbirth among women with hypertensive disorders of pregnancy (HDP). Material and Methods The clinical details of women with HDP having late stillbirth were compared with controls having ...
Manisha Kumar +3 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
ROLE OF FETAL THIGH CIRCUMFERENCE IN ESTIMATION OF BIRTH WEIGHT BY ULTRASOUND [PDF]
, 2005 OBJECTIVE: To evaluate the accuracy and usefulness of predicting birth weight by measuring fetal thigh circumference by ultrasound. METHODS: In 110 pregnant women, fetuses without structural or chromosomal anomalies were studied prospectively and cross ...
N, Varalaxmi, Hebbar, Shripad
core
The position of the testis during the fetal period: an additional parameter to estimate fetal weight
International Brazilian Journal of Urology, 2010 PURPOSE: To establish a correlation between testicular position and fetal weight, in order to provide an additional prenatal parameter for fetal weight estimation. MATERIALS AND METHODS: We studied 288 testes from 144 human fetuses.
Luciano A. Favorito +2 more
doaj +1 more source